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We have 45 molecular pharmacology PhD Projects, Programmes & Scholarships

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molecular pharmacology PhD Projects, Programmes & Scholarships

We have 45 molecular pharmacology PhD Projects, Programmes & Scholarships

Using lipid nano-particles to study G-protein-coupled receptors (GPCRs).

This exciting PhD project in the laboratory of Professor Mark Wheatley, Professor of Biochemical Pharmacology is a joint PhD between Coventry University and Stellenbosch University with the student being registered for a PhD at both universities. Read more

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more
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Molecular basis of brain-immune signaling as a mechanistic target for schizophrenia

Psychotic disorders such as schizophrenia are among the most costly illnesses in terms of personal, economic and societal cost. There is emerging evidence that the complement system that mediates immune and brain cell interactions around synapses is dysregulated in individuals at risk of developing psychosis. Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more

Sciences Research Opportunities at the University of East Anglia

UEA is a top tier, research-led university committed to making a substantial impact on global challenges facing society for over 50 years. Read more

MScR - Astrocyte mechanisms in depression

Depression is the most common mental health illness affecting about 20% of the population at least once in their lifetime. Depression has been proposed to be a result of a decreased level of brain monoamines such as serotonin. Read more

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Transcriptome biomarkers and mechanisms of chemoresistance

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Application and development of bioinformatics and network theory methods in cardiovascular disease research and pharmacovigilance

To be able to discover novel drug targets we aim to develop software based on network theoretic approaches that are capable to identify mediators and pathways involved in the pathomechanism of various cardiovascular diseases by the analysis of datasets assessed with high throughput molecular biological techniques (e.g. Read more

MScR - Determining the genetic and circadian basis of bipolar disorder using Drosophila

Circadian rhythms and sleep are evolutionarily conserved from fruit flies (Drosophila) and are fundamental as well as vital to biology and health (Jagannath et al., 2017; Menet and Rosbash, 2011). Read more

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