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monoclonal antibodies PhD Projects, Programs & Scholarships

We have 9 monoclonal antibodies PhD Projects, Programs & Scholarships

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  (A*STAR) Engineering of virus-like particles and novel multimeric assemblies as scaffolds for presentation of viral antigens
  Prof J P Derrick, Dr F Hayes
Application Deadline: 31 January 2019
This project will use structural vaccinology to investigate the potential for de novo engineering of large, synthetic macromolecular assemblies.
  Dissecting the neutralising antibody response to the porcine reproductive and respiratory syndrome virus to identify novel vaccine targets
  Prof R Owens, Dr S Graham, Dr J Grimes, Prof John Hammond
Application Deadline: 25 January 2019
Porcine reproductive and respiratory syndrome (PRRS) is the most important infectious disease affecting the global pig industry.
  Biological significance, predictive value and targeting of the HER family members in pancreatic cancer
  Prof H Modjtahedi
Applications accepted all year round
Despite major advances in imaging technologies, surgery, chemotherapy, radiotherapy and targeted therapy of cancer in the last few decades, pancreatic cancer remains as one of the most aggressive and fatal types of human cancer.
  PhD studentship: Investigating whether anti-VEGF treatment can cause the switch to VEGF-independent signalling and metabolic reprogramming in intraocular cells
  Dr H Jia
Application Deadline: 11 February 2019
A 3-year full-time PhD studentship is available at the Division of Biotherapeutics, National Institute for Biological Standards and Control (NIBSC), in collaboration with the Division of Medicine, University College London (UCL).
  (BBSRC DTP CASE) Native Mass Spectrometry approaches for Electron and Photon mediated Top Down Sequencing of Biotherapeutics
  Prof P Barran, Dr B Bellina
Application Deadline: 31 January 2019
In this project we propose to develop electron and photon mediated top-down sequencing methods to analyse recombinant biological therapeutics including monoclonal antibodies (mAbs) and adeno-associated viral (AAV) vectors.
  Airway, Liver and Muscle Gene Transfer to Create Therapeutic Protein Factories: utilising experience of in vivo gene transfer and/or in vivo gene editing to understand and manipulate the factors required for effective expression and secretion of therapeutic proteins
  Dr S Hyde, Dr D Gill
Application Deadline: 26 July 2019
We are focusing on strategies to deliver therapeutics via in vivo delivery of gene transfer vectors to generate ectopic “protein factories” capable of secreting therapeutic proteins into both the lung lumen and the systemic circulation.
  Immune Development in a Piglet Model of Environmental Enteric Dysfunction
  Dr M Lewis, Prof G Gibson
Applications accepted all year round
Summary. Environmental enteric dysfunction (EED) affects 200 million children in low- and middle-income countries and has extremely detrimental consequences for long-term health.
  Tetraspanin structure and function
  Dr L J Partridge
Applications accepted all year round
The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  PhD in Infection & Immunity - Modifying human cytomegaloviruses to drive expansion of effector natural killer and cytotoxic T cells
  Dr E Wang, Dr R Stanton
Application Deadline: 27 February 2019
Natural Killer (NK) cells and CD8+ cytotoxic T lymphocytes (CTL) are immune cells known to kill cancerous and virus-infected cells and are being used to treat forms of these diseases.
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