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monoclonal antibodies PhD Projects, Programs & Scholarships

We have 14 monoclonal antibodies PhD Projects, Programs & Scholarships

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  Bispecific monoclonal antibodies for cancer immunotherapy
  Prof W Bodmer, Prof P McHugh
Application Deadline: 10 January 2020

Funding Type

PhD Type

THE PROJECT. Monoclonal antibodies (MCAs) are now widely used for cancer therapy. DNA recombinant technology enables the production of MCAs that target cancer specific determinants and immune cells, attracting them to the cancer cells and so killing them.
  Type 1 diabetes; novel insights from molecular analysis of single B cells.
  Prof K Gillespie
Application Deadline: 25 November 2019

Funding Type

PhD Type

Overview. The University of Bristol is offering a 3.5 year full time PhD to start in 2019. This studentship is funded through GW4 BioMed MRC Doctoral Training Partnership.
  In silico design of high-affinity recombinant antibodies
  Dr P Mulheran, Dr V A Ferro
Application Deadline: 30 November 2019

Funding Type

PhD Type

Currently there is a trend to move from small drug molecule therapy to use of biologics such as monoclonal antibodies (mAb).
  Chimeric Antigen B Cell (CAR B Cell) Therapy for Targeted Therapeutic and Prophylactic Vaccination
  Prof L Seymour, Prof S Draper
Application Deadline: 10 January 2020

Funding Type

PhD Type

Lead supervisor. Prof Len Seymour, Department of Oncology, University of Oxford. Co-supervisor. Prof Simon Draper, Jenner Institute, University of Oxford.
  Antibody-drug conjugates (ADCs) for the treatment of solid tumours
  Dr S Karagiannis, Prof J Downward
Application Deadline: 29 November 2019

Funding Type

PhD Type

An Antibody-Drug Conjugate (ADC) comprises an antibody targeted toward a tumour cell surface antigen, coupled through a chemical linker to a highly-cytotoxic drug.
  (BBSRC DTP) Development of anti-cancer agents and biomarkers that target intrinsically disordered regions of transcription factors and protein kinases
  Prof J Waltho, Dr A Almond
Application Deadline: 31 January 2020

Funding Type

PhD Type

The controlled manipulation of transcription factors, protein kinases and protein phosphatases is central to improving our understanding of cellular processes and, importantly, in the development of next-generation therapeutics for a variety of cancers.
  (BBSRC DTP CASE) Understanding and predicting the immunogenicity of therapeutic protein products
  Prof J P Derrick, Dr R Dearman
Application Deadline: 31 January 2020

Funding Type

PhD Type

Biopharmaceuticals, or therapeutic protein products (TPPs) have been in widespread clinical use for several decades. They comprise a wide range of pharmaceutical products, from vaccines to hormones, cytokines and monoclonal antibodies.
  Optimisation and Preclinical Evaluation of Targeted Nanoformulations of Anti‐TNF‐α Therapeutics for the Treatment of Inflammatory Bowel Disease (IBD)
  Dr Z Ramtoola, Dr B Kirby
Application Deadline: 2 December 2019

Funding Type

PhD Type

Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition that affects the gastrointestinal tract (GIT) of the patient and comprises of Crohn’s disease (CD) and ulcerative colitis (UC).
  (BBSRC DTP) Developing a whipworm vaccine composed of virus-like particles expressing Trichuris T cell epitopes
  Prof K Else, Prof J P Derrick
Application Deadline: 31 January 2020

Funding Type

PhD Type

Vaccination is one of the greatest advances in global health; however most successful vaccines have been made empirically. We still have little insight into how many vaccines work and the mechanisms by which they trigger protective immune responses.
  T cell receptor binding affinity and immune activation in chronic inflammatory disease. (#202006)
  Dr L Jostins-Dean, Prof M Dustin
Application Deadline: 10 January 2020

Funding Type

PhD Type

Activation of immune cells, and in particular the activation of T cells by antigens, has been shown to play a key role in the onset of a range of chronic inflammatory disorders, including inflammatory bowel disease and rheumatoid arthritis.
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