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mouse PhD Projects, Programs & Scholarships

We have 102 mouse PhD Projects, Programs & Scholarships

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  Investigation of the anti-inflammatory effect of curcumin in a mouse model of chronic neuroinflammation – a route for a cure for Alzheimer’s disease?
  Dr E Gyengesi, Prof GM Muench
Applications accepted all year round
This project will investigate the effect of chronic glial activation on brain structure and function, and test the efficacy of two cytokine-suppressive anti-inflammatory drugs (CSAIDs) against chronic glial activation and the resulting neuronal damage.
  Applying AI to quantifying gait and joint loading in a mouse model for knee osteoarthritis using biplanar X-Ray videography, machine learning and force recordings
  Dr K D'Aout, Dr Y Zheng, Prof G Bou-Gharios
Application Deadline: 12 April 2019
Osteoarthritis (OA) is a joint disease leading to impaired function and changes in gait. Several mouse models for OA exist, but exactly how gait and joint function is affected by the disease in these models is unknown.
  Defining the metabolic determinants of intestinal stem cell homeostasis
  Dr A Rufini, Prof F Giorgini
Application Deadline: 5 May 2019
The intestine is the fastest renewing organ. This ability is enabled by the presence of fast proliferating intestinal stem cells (ISCs) that reside in the crypts of Lieberkühn at the base of the intestinal villi.
  Clinical Genetics: Building the skull – normal and abnormal development
  Prof A Wilkie, Dr S Twigg
Application Deadline: 26 July 2019
Working closely with the craniofacial teams based in Oxford and other UK units, we specialise in the application of whole exome and genome sequencing to children born with a serious malformation of the skull termed craniosynostosis.
  Genetics of inherited cardiovascular disease: Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
  Prof H Watkins, Prof H Ashrafian, Prof C Redwood, Prof M Farrall
Application Deadline: 26 July 2019
Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
  Is there a future for the harvest mouse in arable farmland?
  Dr T Reader
Applications accepted all year round
Project Overview. Small mammals, including the enigmatic harvest mouse (Micromys minutus), have long been associated with cereal farming.
  PhD in Dementia Research - Role of a mouse ortholog of CR1 (crry) in the 3xTG model of Alzheimer’s Disease (AD)
  Prof B Paul Morgan, Dr T Hughes
Application Deadline: 31 March 2019
Several genes of the pro-inflammatory complement system, including CR1, Cr1L, Clu and C3 have been linked to AD. However, there remains a yawning gap in our understanding of how proteins derived from these genes impact risk of AD.
  Functional and structural studies of rod-like structures regulated by the dose and de-ubiquitinating activity of USP25, a gene with roles in Down Syndrome associated diseases
  Prof D Nizetic
Application Deadline: 31 March 2019
Barts and The London School of Medicine and Dentistry at Queen Mary University of London and A*STAR PhD Studentship. Functional and structural studies of rod-like structures regulated by the dose and de-ubiquitinating activity of USP25, a gene with roles in Down Syndrome associated diseases.
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round
Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  Development of the hematopoietic/ immune system in the embryo: obtaining a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development
  Prof M DeBruijn
Application Deadline: 26 July 2019
Development of the hematopoietic/ immune system in the embryo. Our aim is to obtain a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development and determine the contribution of these cells to the emerging hematopoietic and immune systems of the embryo.
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