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muscle PhD Projects, Programmes & Scholarships
We have 115 muscle PhD Projects, Programmes & Scholarships
Extra-pulmonary characteristics of people with COPD and lung hyperinflation and the effects of lung volume reduction
For some people with chronic lung disease high lung volumes (hyperinflation) contribute to extreme breathlessness, severely curtailed exercise capacity… Read more
Investigating the efficacy of urine, tissue and blood-based biomarkers for the detection of non-muscle invasive bladder cancer (recurrence/progression)
The Maelor Academic Unit of Medical & Surgical Sciences (MAUMSS) is a novel initiative by the Betsi Cadwaladr University Health Board (BCUHB), and is designed to encourage and support research within the Health Board and to promote academic activity, basic science and clinical research across North Wales (UK) and beyond. Read more
Do patients with anterior cruciate ligament (ACL) tears demonstrate muscle strength deficits of the hip, knee, and ankle muscles?
Anterior cruciate ligament injuries are common with a median annual incidence of 0.03% per person overall and up to 3.7% in professional athletes (1). Read more
Making and breaking myosin filaments: How smooth muscle cells modulate their contractile behaviour.
Smooth muscle is critically important in a range of functions, from maintaining blood pressure, to squeezing food through the gut and many more. Read more
Pathophysiology of intensive care acquired muscle weakness - the role of mitochondrial dysfunction
Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University. Our research group is currently seeking a highly motivated Ph.D. Read more
Multi-organ signalling and diseases. How maintaining skeletal muscle mass impacts the development of liver diseases
Skeletal muscle has a number of roles in the human body beyond locomotion. It has a vital role in controlling the metabolic activity the organism. Read more
Understanding the physiological and metabolic health effects of Vortex Wave Circulation therapy
The human musculoskeletal system undergoes several age-related alterations, including reductions in muscle mass and function (termed ‘sarcopenia’). Read more
Modulation of Smooth Muscle Cell Function by Neutrophil Microvesicles
The leading cause of death globally is cardiovascular disease (CVD), according to the World Health Organisation. Atherosclerosis is the underlying cause of most of these. Read more
Muscle function during running
The anatomy of the legs is complex with multiple muscles that are (anatomically) capable of flexing and extending the limb joints. Read more
Investigating the role of Aquaporins in age related diseases
Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more
Investigating the roles that G protein coupled receptors play in hypertension
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
Muscle-strengthening physical activity: determinants, mechanisms, and intervention effects on health using behaviour change theory
The World Health Organisation physical activity guidelines include recommendations for aerobic and muscle strengthening physical activity (MSPA). Read more
(VIDA DTC) Role of arterial smooth muscle and pericyte dysfunction towards brain waste clearance in Alzheimer’s Disease
Chronic hypertension causes functional and anatomical rarefaction of the cerebral blood vessels and is the main risk factor after age for vascular dementia and stroke. Read more
Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle
Research Group:
Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more
An evaluation of biochemical and haemostatic function in patients with non-muscle invasive bladder cancer (NMIBC).
The Maelor Academic Unit of Medical & Surgical Sciences (MAUMSS) is a novel initiative by the Betsi Cadwaladr University Health Board (BCUHB), and is designed to encourage and support research within the Health Board and to promote academic activity, basic science and clinical research across North Wales (UK) and beyond. Read more