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"muscular" AND "dystrophy…×
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muscular dystrophy PhD Projects, Programs & Scholarships

We have 6 muscular dystrophy PhD Projects, Programs & Scholarships

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  MRC DiMeN DTP: Dissecting INPP5K function: cell biology, structural determination by X-ray crystallography and enzymology of a key protein implicated in muscular dystrophy, insulin signalling, spastic paraplegias and Parkinsonism
  Dr L Swan, Dr S Antonyuk, Dr M Stagi
Application Deadline: 21 January 2019
The Swan laboratory (https://www.researchgate.net/profile/Laura_Swan), specialists in phosphoinositide lipid biology and the cell biology of membrane trafficking, in collaboration with international teams of clinicians and scientists, have recently discovered that mutations in a specific phosphatase cause a congenital muscular dystrophy with short stature, brain and eye manifestations (papers.
  Novel therapeutic approaches for the treatment of Duchenne muscular dystrophy
  Prof S Winder
Application Deadline: 23 January 2019
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene leading to loss of the cytoskeletal protein dystrophin.
  Gene and Cell Therapy For Muscular Dystrophy, Muscular Atrophy, Diabetes and Metabolic conditions
  Dr K Foster
Applications accepted all year round
Skeletal muscle development is a complex process and a number of regulatory factors for the different steps involved in stem cell activation and proliferation through to multinucleated, post-mitotic cells have been identified.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round
The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Stem cell binding to the endothelium during extravasation
  Prof G Cossu, Prof N Tirelli
Applications accepted all year round
In a previous clinical trial carried out by the team (Cossu et al. 2015), HLA-matched, donor mesoangioblasts (pericyte-derived myogenic progenitors) were infused intra-arterially to patients with Duchenne muscular dystrophy.
  MRC Precision Medicine DTP: 3D modelling of changes in genome architecture in development and disease
  Research Group: Institute of Cell Biology
  Prof E Schirmer, Dr D Marenduzzo
Application Deadline: 7 January 2019
Background. Defects in spatial genome organisation have recently been linked to human disease and the National Institutes of Health, USA director speculated that most as yet unidentified disease alleles will occur in non-coding genome regions.
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