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myeloma PhD Projects, Programmes & Scholarships
We have 9 myeloma PhD Projects, Programmes & Scholarships
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Validation of TRAF6/PD-L1 inhibition in pre-clinical models of multiple myeloma: implications for combinational immunotherapy
Programmed death-ligand 1(PD-L1), a negative regulator of the immune system, is highly expressed in newly-diagnosed and relapsed multiple myeloma patients, and its expression is associated with suppressed anti-tumour immunity. Read more
Role of tumour directed T cells in smouldering myeloma
The UCL Myeloma and Tumour Immunology groups are seeking a talented and enthusiastic PhD candidate to lead a project to identify and characterise tumour directed T cells in the bone marrow environment of patients with smouldering myeloma. Smouldering myeloma is a pre-cancerous condition that carries a 50% risk (over 5 years) of developing into the bone marrow cancer called multiple myeloma. Read more
The role of Cks1b in drug resistance in multiple myeloma
Multiple myeloma is a cancer of the bone marrow. Despite marked improvements in survival over the last two decades, it remains incurable. Read more
An interdisciplinary approach to tackling the problem of late Myeloma diagnosis.
There are two parallel studentships on offer. One (this project) is a wet lab project and the other is a bioinformatics project. Both are addressing the fact that multiple myeloma (MM) (a blood cancer of antibody producing cells) is nearly always diagnosed late. Read more
Understanding metabolism in the blood cancer multiple myeloma and its precursor condition MGUS
Applications will be reviewed until a suitable candidate is appointed and funding is available. Read more
A combined bioinformatic and health economic approach to tackling the problem of late Myeloma diagnosis.
There are two parallel studentships on offer. This one is a bioinformatics-based project. The other (separate FindaPhD entry) is a wet lab project. Read more
Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
4-year PhD Studentship: The bone marrow-derived stromal cells – a therapeutic target in haematological malignancy
Bone marrow consists of blood stem cells known as haematopoietic stem cells (HSC) embedded in a matrix of diverse cell populations referred to as the bone microenvironment or ‘niche’. Read more
Macrophage driven therapy resistance in AML: from macrophage subset characterisation to therapeutic targeting.
Research Group:
Molecular Mechanisms and Long Term Conditions
Reference. SHLS20065. Background. Acute Myeloid Leukaemia (AML) is a common blood cancer in adults; with its incidence increasing with age, AML cases are predicted to double by 2030. Read more
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