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natural product PhD Projects, Programs & Scholarships

We have 31 natural product PhD Projects, Programs & Scholarships

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  Engineering Actinobacteria to enhance natural product biosynthesis
  Dr H O'Hare
Application Deadline: 6 January 2019
The Actinobacteria are important producers of approved drugs (>$1 billion dollars in 2016) but low yields of most natural products are a significant barrier to drug discovery, development and commercialisation.
  Streptomyces venezuelae a next-generation cell-factory for synthetic biology
  Dr S Moore
Application Deadline: 18 January 2019
Streptomyces venezuelae a next-generation cell-factory for synthetic biology. Synthetic biology is beginning to explore new cell-factories for opportunities including biofuels and drugs.
  Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A O'Neill
Applications accepted all year round
The World Health Organization (WHO) has declared antimicrobial drug resistance one of the greatest problems currently facing human health, and the situation is especially grave in the case of infections caused by bacterial pathogens.
  Understanding the mechanism of TRPC1/4/5 channel activation by the natural product tonantzitlolone
  Research Group: BBSRC White Rose DTP
  Dr R.S. Bon, Dr S Muench, Dr M Wright
Application Deadline: 7 January 2019
The six human TRPC proteins form tetrameric cation channels that play key roles in cellular signal transduction/integration, and their implication in human disease (including anxiety disorders, renal/breast cancer, heart failure and kidney disease) has led specific TRPC channels to emerge as potential therapeutic targets in both academia and industry.
  (A*STAR) Awakening natural product biosynthetic gene clusters for novel compound discovery using systems and synthetic biology
  Prof E Takano, Prof R Breitling
Application Deadline: 31 January 2019
Recent advances in molecular biology, in particular our improved ability to read and (most importantly) write genomic sequences, have led to renewed excitement in the area of genetic engineering.
  How sustainable is the bioeconomy? A natural capital approach
  Dr J C Stout
Application Deadline: 11 January 2019
We are seeking applicants with Bachelors/Masters degree (2.1 or higher) in natural/environmental science, natural resource management, or similar, preferably with knowledge and experience in ecosystem services, natural capital, bioeconomy, and/or life cycle analysis to do a PhD on “Integrating natural capital into Bioeconomic industrial applications”.
  Validating the use of curcumin in Health and Disease
  Prof R S B Williams
Application Deadline: 15 January 2019
Developing new therapeutic strategies for cancer offers the best hope of continued good health for many people in our society. The natural product curcumin, derived from the spice turmeric, has been effective in several clinical trials relating to cancer and inflammation.
  Targeting the P2X7 purinergic receptor in melanoma (STOKESLU19SF)
  Dr L Stokes, Dr C Morris
Application Deadline: 31 May 2019
There is much research into trying to regain control of cell proliferation or cell death (apoptosis) in cancer. Different strategies exist to do this and a multitude of individual receptor targets are being identified in tumour cell lines and primary cells.
  Engineering lipoglycopeptide biosynthesis to produce new antibiotics
  Research Group: BBSRC White Rose DTP
  Dr R Seipke, Dr G.R. Hemsworth, Dr M E Webb
Application Deadline: 7 January 2019
There is an urgent need for new antibiotics to combat antimicrobial resistance. Most antibiotics originate from Streptomyces bacteria, however the low hanging fruit from this resource has been picked.
  Is the bonding in ionic liquids ordinary or exotic: using molecular dynamics to shed light on these complex systems
  Dr C Evans, Prof A P Abbott
Application Deadline: 21 January 2019
One of the key technologies developed at the University is that of deep eutectic solvents, DESs. The behaviour of solutes in a largely ionic medium governs their reactivity and phase behaviour and this is vital to technologies such as mineral processing, electrochemistry and natural product extraction.
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