Targeting the P2X7 purinergic receptor in melanoma (STOKESLU19SF)
Dr L Stokes, Dr C Morris
31 May 2019
There is much research into trying to regain control of cell proliferation or cell death (apoptosis) in cancer. Different strategies exist to do this and a multitude of individual receptor targets are being identified in tumour cell lines and primary cells.
Brønsted Acid Catalysed Asymmetric Synthesis of Cyclic Ethers
Dr P Clarke
Applications accepted all year round
Over recent years there has been a drive by medicinal chemists to explore more 3-dimensional areas of chemical space. Cyclic ethers, such as the tetrahydropyran (THP) and the tetrahydrofuran (THF) rings, are the most common and 6th most common saturated heterocyclic function present in marketed pharmaceuticals.