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neurodegeneration PhD Projects, Programs & Scholarships

We have 25 neurodegeneration PhD Projects, Programs & Scholarships

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  Genetic and molecular mechanisms of brain structural plasticity and neurodegeneration
  Research Group: BBSRC MIBTP
  Dr A Hidalgo
Applications accepted all year round
The project will test the potential of a molecular mechanism that we recently discovered, in modulating brain structural plasticity versus neurodegeneration.
  Investigating metabolic changes in neurodegeneration
  Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round
This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
  The importance of the DNA damage response in neurodegeneration
  Dr R Tuxworth
Applications accepted all year round
DNA damage occurs in early-stage neurodegenerative diseases. The response of neurons to the damage may contribute to disease progression by inducing senescence, cell-cycle and apoptosis.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Applications accepted all year round
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  Medical Research Council (MRC) Parkinson’s Disease and Neurodegeneration PhD Programme 2019
We are seeking bright and enthusiastic young students to join a new PhD programme at the MRC-PPU dedicated to understanding the cellular mechanisms underlying Parkinson's disease and other neurodegenerative diseases.
  Ion channel regulation in models of neurodegeneration
  Dr M Dallas, Prof G J Stephens, Dr A Bithell
Applications accepted all year round
Ion channels are important regulators of cellular physiology. There is now growing awareness that these proteins are invovled in pathological states, with relation to neurodegeneration voltage-gated potassium and voltage-gated calicum channels have been implicated.
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round
Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  Hypoxia in neurodegenerative diseases: Targets for new therapeutic strategies
  Dr L de Girolamo, Prof S Rutella
Application Deadline: 12 April 2019
The incidence of Parkinson’s and Alzheimer’s disease increases with age, posing serious health concerns. Hypoxia contributes to rapid neurodegenerative decline and impacts on disease progression.
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round
Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  The ubiquitin proteasome system and neurodegenerative disease
  Dr L Bedford
Applications accepted all year round
The mechanisms that cause neurones to die in neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases remain unclear.
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