The deposition of misfolded proteins is a defining feature of many age-dependent human diseases, including the increasingly prevalent neurodegenerative diseases. Read more
Neurodegenerative diseases are one of the greatest health challenges facing our society. This large group of diseases is characterised by the pathological assembly of specific proteins into filaments in the central nervous system. Read more
Almost a million of people in the UK suffer from neurodegenerative disorders. Alzheimer’s disease, dementia with Lewy bodies, and Frontotemporal dementia are the most common causes of neurodegenerative dementias. Read more
Microglia are brain parenchyma-resident macrophages, with important homeostatic functions, clearing away dead cells and debris, and remodelling defunct neuronal connections. Read more
Project Overview. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous environmental pollutants raising concerns due to their potential adverse effects on human health. Read more
We are seeking talented, motivated students with a passion for research in Neuroscience and Neurotrauma to join the team led by Dr Valentina Di Pietro (Dr Valentina Di Pietro - Institute of Inflammation and Ageing - University of Birmingham). Read more
We are seeking talented, motivated students with a passion for research in understanding the causes of neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. Read more
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more
Abnormal filamentous inclusions of the proteins amyloid-beta, tau and alpha-synuclein characterise multiple human neurodegenerative diseases, which are called beta-amyloidoses, tauopathies and synucleinopathies, respectively. Read more
A number of self-funded PhD project positions are available in the theory and application of biologically-inspired “white box” machine learning algorithms… Read more
By 2050 the number of people living with neurodegenerative disorders are set to double. Alzheimer’s disease in particular is set to become a public health emergency. Read more
Although showing diverse symptoms affecting cognition and movement, the brains of patients with neurodegenerative disorders (NDs) display similar neuropathological features namely protein aggregation within the brain. Read more
UK Dementia Research Institute (UK DRI) Centre at Imperial. PhD Studentship in Machine Learning for Genomics. Imperial College London, White City Campus, London, UK. Read more
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