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neurodegenerative PhD Projects, Programmes & Scholarships
We have 66 neurodegenerative PhD Projects, Programmes & Scholarships
We have 66 neurodegenerative PhD Projects, Programmes & Scholarships
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MSc by Research: ADP-ribosylation in dementia and motor neuron disease
ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more
Allosteric targeting of the prostaglandin receptor EP2 to promote neuroprotection against excitoxicity
Research Group:
Wellcome-Wolfson Institute for Experimental Medicine
Excitotoxicity occurs upon brain injury or neurodegenerative diseases and exacerbates associated neuronal damages. The prostaglandin E2 receptor (EP2) has neuroprotective properties against excitotoxicity and novel molecules increasing EP2 activity have been recently discovered. Read more
Understanding the heterogeneity of pathology in dementia with Lewy bodies to aid the interpretation of biomarkers
The primary pathology of dementia with Lewy bodies (DLB) is alpha-synuclein, however multiple studies have demonstrated that Alzheimer’s disease (AD) related pathologies (tau and beta amyloid) play an important role in disease progression driving spread of pathology and accelerating cognitive decline. Read more
Abnormalities in proteins and lipids in Lewy body dementia
Lewy body dementia (LBD) is the second most common form of age-associated dementia disorder. Read more
Self-Navigating Nanocarriers for Intracellular Protein Delivery
Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more
Peptide-based nanoparticles for brain targeted gene delivery
Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more
Investigating the mechanisms of Mitochondrial DNA Repair (Mito-DR)
Applications are invited for a fully-funded three-year PhD to commence in October 2023. The PhD will be based in the Faculty of Science and Health, and will be supervised by. Read more
Understanding non-neurological health care services in people with Parkinson’s
Improving the quality of life of people with Parkinson’s is the ultimate aim of this PhD opportunity. Read more
EPSRC DUNeS: Structure based development of dual specificity inhibitors of NLRP3 and SARM1
Treatment of neurodegenerative disease needs new targets, as current approaches fail to translate in clinical trials. Read more
PhD student (f/m/x) for the study of microbial triggers of intestinal inflammation
The Center for Regenerative Therapies Dresden (CRTD) is a research center at the TU Dresden with currently over 20 research groups and more than 250 employees. Read more
PhD student (f/m/x) for the study of microbial regulation of colorectal cancer development
The Center for Regenerative Therapies Dresden (CRTD) is a research center at the TU Dresden with currently over 20 research groups and more than 250 employees. Read more
Translational potential of novel mitochondrial-targeted nanoparticles encapsulating hydrogen sulphide as modulators of neurological disease.
Neurodegenerative disorders such as Parkinson’s disease occur due to the progressive and irreversible degeneration of nerve cells. Read more
Investigating the oligogenic model of Amyotrophic Lateral Sclerosis (ALS; motor neuron disease, MND)
Research Group:
Neuroscience
Applications are invited for a multidisciplinary PhD studentship funded by the Motor Neurone Disease Association to study the cumulative contribution of coinherited subthreshold amyotrophic lateral sclerosis (ALS) risk gene variants in the development of cellular hallmarks of ALS pathology. Read more
Role of the endosomal pathway in regulating sleep and circadian rhythms
Ageing and many neurodegenerative disorders are characterized by a progressive loss of neurons in particular brain regions leading to behavioural changes including cognitive decline, sleep disruption and circadian dysregulation. Read more
Last chance to apply
PhD Studentship in Motor Neuron Disease – Using a Primate Model to Test Novel Therapies
Overview. Interested in neurodegenerative disorders? This PhD project will use a new primate model of motor neuron disease (MND) to explore disease mechanisms and test novel therapies and biomarkers of disease progression. Read more