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neurodegenerative PhD Projects, Programmes & Scholarships
We have 70 neurodegenerative PhD Projects, Programmes & Scholarships
We have 70 neurodegenerative PhD Projects, Programmes & Scholarships
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Characterising blood-brain barrier formation and function using zebrafish to understand human vascular hyperpermeability
The blood-brain barrier (BBB) is a highly selectively permeable network of blood vessels within the brain. This barrier is essential for central nervous system (CNS) homeostasis by controlling molecular flux between the blood and the brain and protecting it from pathogens and toxins. Read more
The role of extracellular vesicles in lung epithelial cell communication in health and disease
It is estimated that more than 1 bn people suffer from acute and chronic lung problems resulting in millions of deaths every year. Read more
Gene regulation using a CRISPR/Cas9-based histone variant deposition
Pseudogenes are functionless remnants of DNA that are copied from parental genes during evolution. EP400 N-terminal-Like (EP400NL) gene was thought to be a pseudogene, located next to the parental EP400 gene in the chromosome. Read more
Can we repair brain damage using the immune system?
Successful long-term tissue regeneration of any human organ beyond the experimental state remains elusive. Given that the immune system plays a key role in tissue regeneration, including in the CNS, one of the most promising novel approaches is to integrate endogenous immune mechanisms into regenerative strategies. Read more
Microfluidic bioimaging for monitoring protein phase behaviour in biological systems
Over the past decades, protein aggregation has been recognised as one of the causes of neurodegenerative disorders, such as Alzheimer’s disease. Read more
The cellular response to stress: roles in disease and ageing
All living organisms need to adapt to their environment in order to survive and reproduce. They are subjected to many stresses including altered oxygen levels, heat or cold, irradiation, infection and injury. Read more
Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein
Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more
Doctoral College, explore our PhD opportunities across our research centres
The Centre for Stress and Age-Related Disease. The Centre for Stress and Age-Related Disease comprises internationally-recognised researchers working on multidisciplinary projects at the biology-chemistry interface. Read more
Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways
Our research aims to elucidate the molecular and cellular regulation of innate immune signal transduction in the context of infectious, inflammatory and autoimmune disease. Read more
Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes
This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more