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neurodegenerative PhD Projects, Programmes & Scholarships

We have 70 neurodegenerative PhD Projects, Programmes & Scholarships

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We have 70 neurodegenerative PhD Projects, Programmes & Scholarships

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Characterising blood-brain barrier formation and function using zebrafish to understand human vascular hyperpermeability

The blood-brain barrier (BBB) is a highly selectively permeable network of blood vessels within the brain. This barrier is essential for central nervous system (CNS) homeostasis by controlling molecular flux between the blood and the brain and protecting it from pathogens and toxins. Read more

Gene regulation using a CRISPR/Cas9-based histone variant deposition

Pseudogenes are functionless remnants of DNA that are copied from parental genes during evolution. EP400 N-terminal-Like (EP400NL) gene was thought to be a pseudogene, located next to the parental EP400 gene in the chromosome. Read more

Can we repair brain damage using the immune system?

Successful long-term tissue regeneration of any human organ beyond the experimental state remains elusive. Given that the immune system plays a key role in tissue regeneration, including in the CNS, one of the most promising novel approaches is to integrate endogenous immune mechanisms into regenerative strategies. Read more

The cellular response to stress: roles in disease and ageing

All living organisms need to adapt to their environment in order to survive and reproduce. They are subjected to many stresses including altered oxygen levels, heat or cold, irradiation, infection and injury. Read more

Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

Doctoral College, explore our PhD opportunities across our research centres

The Centre for Stress and Age-Related Disease. The Centre for Stress and Age-Related Disease comprises internationally-recognised researchers working on multidisciplinary projects at the biology-chemistry interface. Read more

Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

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