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We have 36 neurodegenerative disease PhD Projects, Programmes & Scholarships

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neurodegenerative disease PhD Projects, Programmes & Scholarships

We have 36 neurodegenerative disease PhD Projects, Programmes & Scholarships

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Alpha-Synuclein Condensates and Synaptic Dysfunction in Parkinson’s Disease

  Research Group: Lautenchlager Lab
Parkinson's disease is the fastest-growing neurodegenerative disorder, with cases projected to more than double by 2050. No disease-modifying treatment strategies exist to date, and mechanistic insights are urgently needed. Read more
 Supervisor: Prof J Lautenschlaeger
 10 July 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Ubiquitin Signalling in Ageing and Age-Related Disease: The Interplay of Genetics, Lifestyle, and Environment

Project Overview. Ageing leads to a progressive decline in essential cellular processes, including protein production, folding, and degradation. Read more
 Supervisor: Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Characterisation of TDP-43 mediated JNK signaling in neurodegenerative diseases ALS and FTD

Lead supervisor. Dr Han-Jou Chen. Co-supervisors. Dr G Evans and Prof Sean Sweeney. The student will be registered with the Department of Biology. Read more
 Supervisors: Dr H J Chen, Dr G Evans, Prof S Sweeney
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microplastics and Nanoplastics as Emerging Risk Factors in Neurodevelopmental and Neurodegenerative Condition

Project Overview. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous environmental pollutants raising concerns due to their potential adverse effects on human health. Read more
 Supervisor: Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting retrosplenial cortex function to improve cognitive deficits in Parkinson’s disease

  Research Group: Neuroscience
Project Description. Parkinson’s disease is the second most common neurodegenerative disorder and is associated with a range of motor and cognitive symptoms. Read more
 Supervisors: Dr M Lelos, Prof S Vann
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PhD Multivalent lipid nanoparticles as a platform for studying cell-nanoparticle interactions in brain disease therapy

Nanoparticles have become essential tools for drug delivery and diagnostics in brain diseases, but their interactions with cells and tissues remain poorly understood. Read more
 Supervisors: Dr CT Tapeinos, Prof J Lawrence
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2025/26. Read more
 Supervisor: Prof I Wood
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the metabolic and transcriptional regulation of lipid-associated macrophages

Project Overview. Metabolic diseases such as obesity, liver steatohepatitis and atherosclerosis are increasingly prevalent worldwide and more emphasis is focused on identifying molecular targets for both prevention and treatment. Read more
 Supervisor: Dr L Dib
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Investigating Glycogen-Dependent Regulation of Microglia Inflammatory Responses

Microglia are the resident immune cells of the central nervous system, responsible for responding to infection and damage in a protective manner. Read more
 Supervisor: Dr A Lloyd
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Unravelling the molecular mechanism underpinning Ubiquitin-like fusion protein proteolysis

The Maniaci Lab tackles one of the big puzzles in cell biology. Read more
 Supervisor: Dr C Maniaci
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Discovering the Biological Role(s) and Proteomic Impact of Non-Canonical Ubiquitylation

Ubiquitylation, the process by which the small protein ubiquitin is attached to target proteins, is a fundamental post-translational modification… Read more
 Supervisor: Dr V De Cesare
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating lysosomal (dys)function in ageing and neurodegeneration

Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more
 Supervisors: Dr S Cogo, Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cellular and molecular mechanisms of Hereditary Spastic Paraplegia

Project Overview. Hereditary Spastic Paraplegias (HSPs) are a group of rare, inherited, neurodegenerative disorders characterised by weakness and tightness of the leg muscles. Read more
 Supervisor: Dr S Cogo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing an advanced microscopy platform to characterise neuronal internalisation and spreading of pathological protein aggregates

PhD studentship in automated fluorescence microscopy to study intercellular aggregate spreading, Imperial College London. Read more
 Supervisor: Dr Y Ye
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Molecular Switch Nanoparticles for Redox-Triggered Drug Delivery

Oxidative stress is a defining feature of several chronic diseases, including cancer, diabetic complications, and neurodegenerative disorders. Read more
 Supervisors: Dr S Carmali, Dr J Coulter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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