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neurogenesis PhD Projects, Programmes & Scholarships
We have 12 neurogenesis PhD Projects, Programmes & Scholarships
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4-year PhD Studentship: Control of neuronal differentiation and ciliogenesis through mineralocorticoid receptor (MR) – Regulatory Factor X (RFX) interaction in embryonic and adult neurogenesis
Glucocorticoid hormones (GCs) are of critical importance for health[1]. They bind to two receptor types in the hippocampus. the mineralocorticoid (MR) and glucocorticoid receptor (GR) which act as ligand-dependent transcription factors[2-4]. Read more
How do hormones regulate memory?
Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression, and impairment of memory. Read more
A role for cholesterol metabolism in neurodevelopmental disorder
Microdeletions and duplications of the chromosome 15q11.2 region have been identified as a high penetrant risk copy number variance (CNV) to autism and schizophrenia. CYFIP1 (Cytoplasmic FMR1-interacting protein 1) is generally believed to be the causal risk gene in this CNV. Read more
Going across temporal scales: how are oscillatory dynamics of protein expression decoded in the expression of downstream genes in neurogenesis?
In recent years, our understanding of gene expression dynamics has been transformed by single-cell, molecular and imaging technologies. It was thought that genes are simply “on” or “off”, but we now appreciate that the dynamics are more complex. Read more
Structural plasticity and regeneration in the Drosophila brain
Does the brain change as we go through life and does this depend on our experiences? What is the impact in the brain of stimulation, activity, exercise… Read more
Neural circuit changes underpinning olfactory learning
Learning is a fundamental feature of brains; they rewire their circuitry to store new information, such as an association between a stimulus and its positive or negative outcome. Read more
4-year PhD Studentship: Towards a model of cerebroventricular development using induced pluripotent stem cell derived organoids
Preterm infants, born at under 32-weeks gestation, are at risk of long-term neurodevelopmental impairment including cerebral palsy and compromised cortical development. Read more
Self funded BMS Project: Neuronal-Src kinases: oncogenes in brain development?
Applications accepted for PhD Only. The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections. Read more
Modelling Setbp1 haploinsufficiency disorder using hESC derived neurons and cerebral organoid cultures
Human brain development is a process tightly controlled by morphogens and transcription factors in a temporal- and spatial-dependent manner. Read more
The role of neural stem cells and new neurons in regulating energy homeostasis
The project combines molecular biology and neuroscience to investigate the role of neural stem cells and new neurons in regulation of body weight. Read more
Unravelling the role of Lrig2 during neuromuscular development
Motor nerves connect the spinal cord and brain with muscles in our face, arms, legs and internal organs. The motor nerves send signals which tell these muscles to contract. Read more
Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways
Our research aims to elucidate the molecular and cellular regulation of innate immune signal transduction in the context of infectious, inflammatory and autoimmune disease. Read more
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