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neuromuscular PhD Projects, Programs & Scholarships

We have 9 neuromuscular PhD Projects, Programs & Scholarships

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  An exciting opportunity to examine lower limb neuromuscular control in patients with diabetes and to develop prehabilitation strategies to improve function and quality of life in this population
  Dr A Mitchell, Dr L Charalambous
Application Deadline: 24 January 2019
Ref. ISPAR-LLN1. Department. Institute of Sport and Physical Activity Research (ISPAR). Please note. Actual location of study will be at the Bedford Campus.
  The role of neuromuscular junction (NMJ) degeneration in age-related loss of skeletal muscle mass and function
  Prof MJ Jackson, Prof A McArdle, Dr A Vasilaki
Applications accepted all year round
The NMJ (or motor endplate) is a highly specialised chemical synapse that transmits action potentials from motor neurons to muscle fibres.
  Force platform assessment of vertical jumping: application to monitoring professional team sport athletes
  Dr P Comfort, Dr J McMahon, Dr P Jones
Applications accepted all year round
Vertical jumping (namely squat, countermovement, and drop vertical jumping) is widely used as a method for monitoring athletes’ neuromuscular function in a range of professional team sports.
  The mechanism, function, and medically-relevant dysfunction of mitochondrial complex I (NADH:ubiquinone oxidoreductase) (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Prof J Hirst
Application Deadline: 30 June 2019
Complex I (NADH:ubiquinone oxidoreductase) catalyses the first step in the respiratory chain and oxidative phosphorylation. NADH oxidation and quinone reduction, coupled to proton translocation across the inner membrane.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round
The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Therapeutic models for Spinal muscular atrophy
  Prof R Yáñez-Muñoz
Applications accepted all year round
Our laboratory works on Gene Therapy in the Central Nervous System and Gene Repair, using novel viral vectors, gene targeting and induced pluripotent stem cells (iPSCs) as core technologies.
  Characterising the human Amyotrophic Lateral Sclerosis (ALS) synaptic proteome
  Dr C Henstridge, Dr T Wishart
Application Deadline: 1 February 2019
Amyotrophic Lateral Sclerosis (ALS) is caused by the breakdown of upper and lower motor neurons leading to the progressive weakness and atrophy of muscle, often resulting in respiratory failure and death within a few years of diagnosis.
  The effect of low protein diet on the development of the musculoskeletal system
  Dr A Vasilaki, Dr K Whysall, Dr I Kanakis
Applications accepted all year round
Age-related sarcopenia is characterised by reduction in the number of myofibres and motor neurons and an additional weakening of the remaining fibres, causing reduction in muscle mass and function.
  Digital assessment and therapy of neurodisability
  Dr P Bentley, Prof E Burdet
Application Deadline: 23 January 2019
The project will investigate cognitive mechanisms, clinical efficacy and practicality of a novel motor rehabilitation system – GripAble (www.gripable.org) - developed by the project team.
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