Investigating modifiers transcripts in models of motor neuron disease
Dr L Murray, Prof T Gillingwater
7 January 2019
The term ‘motor neuron disease’ refers to a group of disorders in which motor neurons are the primary target. The search for therapeutic agents to treat motor neuron disease often focuses on one subtype with a specific cause.
Excitatory interneuron defects in motor neurone disease
Dr J McDearmid, Dr W NORTON
Applications accepted all year round
Amyotrophic lateral sclerosis (ALS) is an untreatable disease that causes degeneration of motor neurons, typically resulting in death within 2-3 years of diagnosis.
Visualizing synaptic AMPA receptors with con-ikot-ikot toxin
Institute of Quantitative Biology, Biochemistry and Biotechnology
Dr J Baranovic, Dr M Horrocks
13 December 2018
AMPA-type glutamate receptors are transmembrane proteins found in the postsynaptic membranes of our central nervous system. They play one of the main roles during excitatory synaptic transmission in the mammalian brain.