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neuronal PhD Projects, Programmes & Scholarships
We have 84 neuronal PhD Projects, Programmes & Scholarships
Neuronal control of appetite: investigating the role of the extracellular matrix in controlling neuronal activity in the hypothalamus
Research Group:
Chemistry and Biosciences
Appetite regulation is complex, and its dysregulation has serious implications for health, being observed in multiple conditions e.g., obesity, anorexia, and type 2 diabetes. Read more
Computational neuroscience: Statistical signal processing for multivariate neuronal data, Neural computing with Spiking neural networks.
Research Group:
Healthcare Engineering
How does the human brain work? As you read this text, the pixels on your screen are converted into a series of spike trains passing along the neural pathways in your brain, allowing you to understand the content. Read more
Unravelling mechanisms of cytoskeletal regulation that control neuronal health and disease
Axons are the slender, often meter-long processes of neurons which electrically wire the brain. These delicate structures are up to a meter long and need to be maintained for decades. Read more
How can we use transcranial ultrasound brain stimulation to restore cellular function in Alzheimer’s disease?
A key feature of Alzheimer’s disease – the leading form of dementia - is diminished neural activity in various brain regions, including those important for memory function such as the hippocampus (Herholz et al., 2007; O’Brien et al., 2010). Read more
Fractional order modelling of neurons
Project Overview. Fractional order calculus (integro-differential equations that are of non-integral order) is an emerging methodology with wide applications across all areas of Physics and Engineering. Read more
Understanding KANK1 contribution to neuronal health and disease.
Motor Neurone Disease (MND) is a catastrophic disease with a 100% fatality rate but is mechanistically poorly understood. Recently, αβ-integrin heterodimers have been implicated in neurodegeneration. Read more
Psychedelic drugs and serotonergic modulation of functional connectivity in neuronal microcircuits
Psychoactive drugs result in profound alterations of our state of consciousness. Well known examples of such drugs are general anaesthetics, in use since mid-19th century, and psychedelics, which are consumed by different societies from times immemorial. Read more
Metabolic Control of Microglia in MS-Associated Cognitive Decline
Multiple sclerosis (MS) is a devastating neurological condition affecting millions worldwide. Cognitive impairment significantly impacts the quality of life of people with MS and is often irreversible. Read more
Investigating Epilepsy Molecular Mechanisms in Patient-Specific Stem Cell Models of SLC6A1 Deficiency
SLC6A1 encodes GAT-1, a voltage-dependent gamma-aminobutyric acid (GABA) transporter that is responsible for the reuptake of GABA from the synapse. Read more
Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder
Tousled-like kinase 2 (TLK2) was recently identified as a novel genetic locus for a neurodevelopmental disorder. Patients predominantly possess de novo mutations in TLK2, leading to a reduction in its expression or kinase activity. Read more
Foundations of large-scale neuronal dynamics: creating links between computational and clinical neuroscience
Models in computational neuroscience remain highly scale-specific, with little or no cohesion between sub-disciplines dealing with different types of neuroimaging datasets. Read more
Cancer Neuroscience: Investigating the impact of non-CNS tumours on neuronal plasticity in the brain
To apply, please contact Dr Graham Sheridan at Graham.Sheridan@nottingham.ac.uk. Cancer is one of the leading causes of death worldwide, resulting in approximately 18 million new cases and 10 million deaths each year. Read more
Applied optogenetics to study the influence of neuronal activity on neurodegeneration
Neurodegenerative diseases represent a significant and growing challenge to global health, affecting millions worldwide. Despite extensive research efforts, the underlying mechanisms of neurodegeneration are not fully understood, and there is a critical lack of effective treatments. Read more
Cell-biological mechanisms mediating primary cilium mediated interpretation of Shh signalling during vertebrate neuronal differentiation
Newborn neurons undergo extensive morphological changes as they polarise to extend axons. In the developing spinal cord, newborn neurons extend axons towards their targets in response to cues from the surrounding tissues. Read more
Characterising a new neuroimmune pathway to treat Alzheimer’s disease. MRC GW4 BioMed DTP PhD studentship 2025/26 Entry,
About the GW4 BioMed2 Doctoral Training Partnership. The partnership brings together the Universities of Bath, Bristol, Cardiff (lead) and Exeter to develop the next generation of biomedical researchers. Read more