We have 27 neurosciences PhD Projects, Programmes & Scholarships



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neurosciences PhD Projects, Programmes & Scholarships

We have 27 neurosciences PhD Projects, Programmes & Scholarships

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Development of a semi-automated CT-brain analysis tool for application to real world clinical cohorts

Commercial partner: Brainomix, Oxford. Background. CT-brain imaging is the standard brain imaging modality used in the NHS and globally and is cheaper and better tolerated than MRI particularly in older, frail, multimorbid patients in whom MRI may be contraindicated. Read more

Faculty of Medicine, Masaryk University

The Biomedical Sciences doctoral degree programme has been created through the merging Medical Biology, Anatomy, Histology, Embryology, and Molecular Medicine, which has been designed in the CEITEC MU research centre to be a robust singular study programme consisting of three disciplines (Cell and Tissue Morphology, Biochemistry and Molecular Biology, and Molecular Medicine). Read more

Metabolic Control of Microglia Regulating Neuronal Functions

Background. Chronic, low grade, inflammation plays a critical role in inflammatory and degenerative central nervous system (CNS) disorders characterised by an irreversible decline of cognitive functions. Read more

Management of Mild Traumatic Brain Injury

(co-supervised with Professor Peter Hutchinson). Although mild Traumatic Brain Injury (concussion) is the commonest form of brain injury, patient pathways are poorly defined, and patients sometimes lack the support required to deal with post-traumatic symptoms. Read more

Investigating gut-immune interactions in Parkinson’s disease

It is now well established that both gastrointestinal dysfunction and immune activation occur in early Parkinson’s disease, and emerging evidence indicates that these processes are linked to faster disease progression. Read more

Identifying Novel Genes and Developing Treatments for Children with Inherited Neuromuscular Diseases

Inherited neuromuscular disorders are disabling, progressive, often fatal conditions, representing an enormous unmet medical need with devastating impacts on affected families, the healthcare system, and the economy. Read more

Functional MRI Imaging in Traumatic Brain Injury

CENTER-TBI is a large European project that aims to improve the care for patients with Traumatic Brain Injury (TBI). The work undertaken in Cambridge will examine the role of MRI in routine TBI imaging and this project will focus on the role of resting state functional MRI in TBI imaging. Read more

Exploring Disease Mechanism in Cerebral Small Vessel Disease Ultrahigh Resolution using 7T MRI

Cerebral small vessel disease (SVD), is a major cause of both stroke and vascular dementia. It describes a process where the small arteries and arterioles in the brain become abnormal, and this leads to both acute and chronic ischaemic damage in the brain. Read more

Development of PET Radiotracers of AMPA

Our aim is to develop novel Positron Emission Tomography (PET) radiotracers for imaging the brain. PET is a non-invasive molecular imaging technique which enables visualization and quantification of various biological targets in vivo (e.g., receptor, enzyme). Read more

Assessing the Disease Severity in CADASIL using Patients iPSC-derived Models of the Neurovascular Unit

CADASIL is a hereditary cerebral small vessel disease caused by mutations in the NOTCH3 gene. Small vessel diseases affect the small penetrating arteries and brain capillaries and patients often suffer of migraine, ischaemic stroke, and cognitive decline. Read more

A Cell Interactome Approach to Model, Characterise and understand Novel Mechanisms of Disease in Progressive Multiple Sclerosis

(co-supervised with A Nicaise and I Mohorianou). Recent work suggests that cellular ageing, known as senescence, of endogenous stem-like cells in the brain may contribute to the chronic inflammation and neurodegeneration seen in people with progressive multiple sclerosis (PMS). Read more

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