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next generation sequencing PhD Projects, Programmes & Scholarships

We have 54 next generation sequencing PhD Projects, Programmes & Scholarships

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We have 54 next generation sequencing PhD Projects, Programmes & Scholarships

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Deciphering a novel anti-ageing epigenetic programme

Over two decades of intense research in the field of epigenetics have produced compelling evidence that chromatin modifications are crucial for processes such as DNA repair, transcription, splicing, mitosis, meiosis, and in the preservation of the epigenetic memory of cells. Read more
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Single-cell analysis of stress memory in plants

Plants are sessile organisms that are known for their adaptive plasticity to the changing environment. Environmental changes cannot only influence gene expression patterns but also affect the stability of the genome. Read more
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The molecular basis of glial cell heterogeneity in human brain

Glial cells constitute a large fraction of the mammalian brain. Although initially considered as non-functional supporter for neuron function, recent studies have revealed that glial cells have critical roles in the brain under both physiological and pathological conditions. Read more

The role mRNA-specific translation during chronological aging

Biological ageing can be thought of as a progressive decline in the ability of an organism to survive stress and disease. It is a complex process which is influenced by both genetic and environmental factors. Read more

Building the skull - normal and abnormal development

Using a combination of patient samples and mouse models, we study the causes and developmental origins of skull malformation. The work ranges from screening human DNA for new mutations, to use of genome editing and single cell transcriptomics to model the developmental causes of these malformations in mice. Read more

How GABA neurones in the DVC control glucose metabolism

The Dorsal Vagal Complex (DVC) of the brain is an important regulator of glucose metabolism and food intake. The Nucleus of the Solitary Tract (NTS) in the DVC senses insulin and triggers a neuronal relay to decrease hepatic glucose production (HPG) in rodents. Read more

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