oligonucleotide PhD Projects, Programmes & Scholarships

We have 5 oligonucleotide PhD Projects, Programmes & Scholarships

Next Generation Oligonucleotide Drugs for Gene Therapy

University of Portsmouth School of Pharmacy and Biomedical Sciences

Synthetic oligonucleotides are short strands of DNA that can be used to treat or manage a wide range of diseases, for example by silencing malfunctioning genes. Read more

Supervisor: Dr D Rusling

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of miRNAs as a new therapeutic tool in the treatment of cardiovascular diseases

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

Ischemic heart diseases and their pathological consequences belong to the leading causes of death worldwide. In the acute treatment of myocardial ischemia one of the most important tasks is the restoration of the tissue perfusion. Read more

Supervisor: Prof P Ferdinandy

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more

Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Chemically Modified Therapeutic Nucleic Acids for Neurological Diseases

University of Southampton Faculty of Engineering and Physical Sciences

Therapeutic oligonucleotides are unique in targeting mRNA particularly those that cannot be addressed by conventional small molecule drugs or therapeutic antibodies, their potential is growing fast. Read more

Supervisor: Mr AS El-Sagheer

31 August 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

The University of Manchester Faculty of Biology, Medicine and Health

Epilepsy is a chronic neurological disease characterised by recurrent spontaneous seizures and cognitive co-morbidities. Current small molecule approaches to treating epilepsy are ineffective in a significant portion of cases, and are associated with substantial adverse effects. Read more

Supervisors: Dr G. Morris, Dr R Wykes, Prof R Baines

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 5 oligonucleotide PhD Projects, Programmes & Scholarships

oligonucleotide PhD Projects, Programmes & Scholarships

We have 5 oligonucleotide PhD Projects, Programmes & Scholarships

Next Generation Oligonucleotide Drugs for Gene Therapy

Development of miRNAs as a new therapeutic tool in the treatment of cardiovascular diseases

Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Chemically Modified Therapeutic Nucleic Acids for Neurological Diseases

Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

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