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ovarian PhD Projects, Programs & Scholarships

We have 17 ovarian PhD Projects, Programs & Scholarships

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  Activation of targeted DNA Damage Response as a novel therapy for Ovarian Cancer
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round
High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer and accounts for 70% of all ovarian cancer deaths.
Details
Type/Funding
  Targeting the Achilles’ heel – dissecting drug resistance in ovarian cancer
University of Dundee School of Medicine
  Dr G Smith, Dr M Ferguson
Applications accepted all year round
Ovarian cancer, the most common cause of gynaecological cancer death, is frequently diagnosed when the disease is already advanced, when surgery is not always possible.
Details
Type/Funding
  Therapy-induced senescence and stemness in ovarian cancer
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Prof R. Pearson, Dr K Chan
Applications accepted all year round
Cellular senescence is a stress response characterized by a robust cell cycle arrest and is a brake for malignant transformation.
Details
Type/Funding
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
University of Leeds Faculty of Medicine and Health
  Dr S Bell, Prof C A Johnson
Applications accepted all year round
Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
Details
Type/Funding
  Regulation of gene expression in Drosophila ovarian germline stem cells
University of Manchester Faculty of Biology, Medicine and Health
  Prof H Ashe, Prof M Ashe
Applications accepted all year round
Drosophila germline stem cells (GSCs) are a premier model for understanding stem cell regulation. Upon division, one GSC daughter remains a stem cell, whereas the other differentiates into a cystoblast (CB).
Details
Type/Funding
  Investigating the modulation of cellular responses as a consequence of long term Poly ADP Ribose Polymerase (PARP) inhibition therapy
Kingston University Faculty of Science, Engineering and Computing
  Dr T Gaymes
Applications accepted all year round
Approximately 30 years ago, Poly ADP Ribose Polymerase (PARP) activity was shown to play a critical role in the processes of DNA repair in nucleated cells.
Details
Type/Funding
  Characterize the role of Treacle (TCOF1) in AKT-regulated ribosome biogenesis
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Prof R. Pearson, Dr J Kang
Applications accepted all year round
Ribosomes are essential for cell growth and proliferation, and their biogenesis requires exquisite regulation.
Details
Type/Funding
  Defining the ‘molecular signature’ of PARP inhibitor sensitivity in blood cancers
Kingston University Faculty of Science, Engineering and Computing
  Dr T Gaymes
Applications accepted all year round
Despite significant advances in the understanding of the biology of blood cancers, identification of the most effective and safe form of treatment continues to present a formidable challenge to clinicians.
Details
Type/Funding
  Statistical inference for response-adaptive clinical trials
Medical Research Council (Cambridge) MRC Biostatistics Unit
  Dr D Roberston, Dr S Villar, Dr A Mander
Application Deadline: 3 January 2019
Clinical trials typically randomise patients to the different treatment arms using a fixed randomisation scheme, such as equal randomisation.
Details
Type/Funding
  Impact of targeted therapy on the melanoma immune microenvironment
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Dr K. Sheppard, Prof G. McArthur
Applications accepted all year round
The treatment of melanoma is undergoing a fundamental change due to the success of both targeted therapies directed at the MAPK/ERK pathway and immunotherapies.
Details
Type/Funding
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