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oxidative stress PhD Projects, Programs & Scholarships

We have 21 oxidative stress PhD Projects, Programs & Scholarships

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  Metabolic rewiring in liver cancer: Role of oxidative stress and the Nrf2 pathway
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Many of the major risks factors for developing liver cancer such as alcohol, obesity, smoking and toxin exposure share in common a role for oxidative stress.
  Effect of nanoparticles on cellular conditions in lymphocytes and germ cells in vitro
  Research Group: Chemistry and Biosciences
  Prof D Anderson, Dr M Najafzadeh
Applications accepted all year round

Funding Type

PhD Type

The use of metals such as silver (Ag), gold (Au) and copper (Cu) as nanoparticles (NPs) and other chemicals such as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (Najafzadeh et al., 2016) in medical and lifestyle applications has exponentially increased in recent years, yet little is still known about their impact on DNA and RNA in somatic as well as in germ cells (Habas et al 2018).
  Targeting mitochondrial dynamics to prevent Parkinson’s disease
  Prof A Sivaprasadarao, Dr R.S. Bon
Application Deadline: 1 June 2020

Funding Type

PhD Type

A common feature of Parkinson’s disease (PD) is the presence of alpha-synuclein protein aggregates in the brains of affected patients.
  Understanding how p18/LAMTOR1 maintains the pulmonary endothelium – a potential therapeutic target for chronic respiratory diseases
  Research Group: Biomedical Research Group
  Dr H Chichger
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Elucidating the Role of Aging on Topoisomerase II Beta Expression and Repair in Neurones (Ref: SF20/APP/PADGET)
  Dr K Padget
Applications accepted all year round

Funding Type

PhD Type

Neurons show high levels of metabolic activity which results in the production of high levels of oxidative stress. However this is counterbalanced by a robust repair system in these cells.
  Exploring the functional and pathological relevance of DJ-1 phosphorylation
  Prof F Giorgini
Application Deadline: 7 June 2020

Funding Type

PhD Type

DJ-1 is a small conserved protein of 189 residues which is ubiquitously expressed and primarily localized to the cytoplasm, but also found in the nucleus and associated with mitochondria.
  The role of functional foods in modulating the adaptive response to training (Ref: SF20/SER/HOWATSON)
  Prof G Howatson
Applications accepted all year round

Funding Type

PhD Type

There is growing body of evidence to suggest that the use of bioactive foods can be beneficial in the management of post-exercise declines in muscle function.
  Proteomic approach to understand mitochondrial quality control under normal and stress conditions
  Dr H Lu, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Defects in protein quality control lead to the accumulation of misfolded and damaged proteins, which play an important role in many diseases (e.g.
  Bacterial lipocalins: Novel role in bacterial protection against antibiotic-induced membrane lipid peroxidation
  Research Group: Centre for Experimental Medicine
  Prof M Valvano
Applications accepted all year round

Funding Type

PhD Type

We recently discovered that bacteria can resist antibiotics by mechanisms operating extracellularly in response to near-lethal antibiotic concentrations.
  Investigating Therapeutic Effect of Different Antioxidants in Friedreich’s Ataxia (FRDA)
  Dr S Anjomani-Virmouni
Applications accepted all year round

Funding Type

PhD Type

Friedreich’s ataxia (FRDA) is an inherited neurodegenerative disorder caused by epigenetic silencing of the frataxin gene. It is the most common inherited ataxia, affecting 1:50,000 Caucasians, and is characterised by neurodegeneration, cardiomyopathy, diabetes mellitus and skeletal deformities.
  Targeting Connexin and Pannexin channel signalling in Diabetic Retinopathy
  Research Group: Molecular Mechanisms and Long Term Conditions
  Dr P Martin, Dr X Shu, Prof N Strang
Applications accepted all year round

Funding Type

PhD Type

Reference. SHLS20042. Diabetic retinopathy (DR) is a microvascular consequence of diabetes mellitus (both Type 1 and Type 2) affecting more than a third of diabetics (affecting an estimated 100million people worldwide).
  Investigating the chemistry of antioxidants and polysaccharides present in date-fruit (Phoenix dactylifera) as a novel/potential therapies for neoplastic and infectious diseases.
  Dr H Morgan
Applications accepted all year round

Funding Type

PhD Type

Date-fruit contains vast amount of phenols; approx. 80400µmol/100g, which portray antioxidant abilities.
  Role of telomere attrition in cardiometabolic disease risk
  Dr J Buxton, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

Common conditions such as Type 2 diabetes (T2D) and coronary artery disease (CAD) are complex disorders caused by a myriad of interacting genetic and lifestyle factors.
  PhD Studentship: Influence of phytochemical administration on inflammation, redox balance and muscle regeneration following exercise in older and younger adults
  Dr T Clifford
Application Deadline: 26 June 2020

Funding Type

PhD Type

Reference number. SSEHS/TC. Start date of studentship. 1 October 2020. Closing date of advert. 26 June 2020. Interview date. July/August.
  Characterising human metalloproteome to disrupt metal toxicity induced neurodegeneration (Ref: SF20/APP/SOUNDARARAJAN)
  Dr M Soundararajan
Applications accepted all year round

Funding Type

PhD Type

Metal accumulation and biometal dyshomeostasis in the nervous system leads to loss of neuronal function.
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