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We have 15 oxidative stress PhD Projects, Programmes & Scholarships

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oxidative stress PhD Projects, Programmes & Scholarships

We have 15 oxidative stress PhD Projects, Programmes & Scholarships

Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

Investigating the role of Aquaporins in age related diseases

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more

The BCAT1 CXXC Motif and Oncogenesis in Acute Myeloid Leukaemia

The BCAT1 gene is implicated in the pathogenesis of many cancer types, including acute myeloid leukaemia (AML)1–4. Recently, our group identified a novel antioxidant role for BCAT1 in AML cells5. Read more

Chaperones and the response to protein misfolding stress

Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more

The role of ageing cutaneous fibroblasts in modulating melanocyte pigmentation

  Research Group: Centre for Skin Sciences
The aim of the project is to gain an understanding of how aged skin fibroblasts and their secretory phenotype contribute to ageing pigmentation and commonly associated disorders. Read more

Artemisinin Derivatives to Fight Malaria

A self-funded PhD position is available in the Fielding and Ismail research groups. We investigate unpaired electron species that play an important role in biological and materials chemistry. Read more

Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more
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