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oxidative stress PhD Projects, Programs & Scholarships

We have 30 oxidative stress PhD Projects, Programs & Scholarships

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  MRC DTP 4 Year PhD Programme: Investigating the role of oxidative stress and anti-angiogenic factors in preeclampsia utilising physiological and 3D-cell models.
  Prof C Murdoch, Dr C Henderson
Application Deadline: 18 January 2019
Preeclampsia occurs in 3-8% of all pregnancies causing rapid hypertension and kidney dysfunction in pregnant woman which is difficult to predict and untreatable.
  Metabolic rewiring in liver cancer: Role of oxidative stress and the Nrf2 pathway
  Dr A. Cox
Applications accepted all year round
Many of the major risks factors for developing liver cancer such as alcohol, obesity, smoking and toxin exposure share in common a role for oxidative stress.
  Development of novel transgenic fluorescent biosensor bivalves (oyster and mussel) for detecting oxidative stress - PhD (Funded)
  Dr T Kudoh, Prof C R Tyler
Application Deadline: 30 January 2019
Supervisors. Dr Tetsu Kudoh, University of Exeter. Professor Charles Tyler, University of Exeter. Dr Tim Bean, Centre for Environment, Fisheries & Aquaculture Science.
  Induction of yeast prions by oxidative stress
  Prof C M Grant, Prof M Ashe
Applications accepted all year round
Prions are novel protein-only infectious agents associated with a group of transmissible neurodegenerative diseases typified by human Creutzfeldt Jakob Disease (CJD).
  MRC DiMeN Doctoral Training Partnership: Determination of how killer pathogenic fungi evade human innate immune defences
  Prof J Quinn, Dr S Johnston
Application Deadline: 21 January 2019
More people die from fungal infections than from malaria, tuberculosis, or ‘superbugs’ such as MRSA. Candida species are an important group of human fungal pathogens causing over 400,000 life threatening infections per year.
  Synthesis and study of metal chelators against neurodegenerative diseases and cancer (ref:SF18/APP/Tetard)
  Dr D Tetard
Applications accepted all year round
Because of the involvement of metal in numerous biological processes, in particular in oxidative stress and enzymatic action, the study of metal chelators as potential therapeutic agents has been growing.
  Role of the antioxidant transcription factor Nrf2 in determining susceptibility to non-alcoholic steatohepatitis in a human liver cell model
  Prof J D Hayes, Dr J F Dillon
Applications accepted all year round
Non-alcoholic fatty liver disease (NAFLD) is a major public health concern in the UK as it is associated with obesity, and has huge economic significance.
  What constitutes ‘effective’ exercise for Alzheimer’s Disease? A project to assess if exercise can alter markers of disease pathology
  Dr S Aldred
Applications accepted all year round
Alzhemier’s Disease (AD) is the most common form of dementia in the UK. There is no one cause, it is a multi-factoral disease. Oxidative stress is believed to be one of the factors or pathologies which contributes to AD.
  A hidden biochemical pathway in the chemical pathology of diabetes (HAMILTONCU19SF)
  Dr C Hamilton
Applications accepted all year round
In humans, the cysteine-containing tripeptide glutathione (GSH) is an essential thiol cofactor that maintains an intracellular reducing environment to protect against oxidative stress reactive oxygen species, which cause lipid, protein & DNA damage.
  (BBSRC DTP) Elucidating the responses to nascent protein misfolding and aggregation stress
  Prof C M Grant, Prof S Hubbard, Prof M Ashe
Application Deadline: 31 January 2019
The aim of this study is to characterize the proteins that aggregate during nascent protein misfolding and to investigate how cells mitigate the damaging effects of aggregate formation.
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