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p53 PhD Projects, Programs & Scholarships

We have 5 p53 PhD Projects, Programs & Scholarships

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  Exploration of novel approaches to anti-cancer treatment: manipulation of mutant p53
  Prof Y. Haupt, Dr S. Haupt
Applications accepted all year round
P53 is the most mutated gene in human cancer, affecting about half the cases of human cancer. We have recently identified novel regulators of mutant p53 using sophisticated loss of function whole genome high through put screen (image 1).
  Defining the role of p53 in cancer immunotherapy
  Prof Y. Haupt, Dr S. Haupt, Dr P. Neeson
Applications accepted all year round
Despite clear evidence of an association between the tumour suppressor p53 and immunity, a gap in knowledge exists regarding its role in modulating immune responses, or its value in predicting patient responses to immunotherapy.
  Regulation of BCR signalling by DNA damage response and P53 protein
  Prof M Mráz
Application Deadline: 15 March 2019
We are looking for a motivated PhD student that would like to work on the following project funded by the ERC (European Research Council) Starting grant.
  Characterisation of cell death mechanisms in cancer: protein interactions in p53/PERP-mediated apoptosis
  Prof L Paraoan, Dr I Prior
Applications accepted all year round
Apoptosis or programmed cell death is a tightly regulated intrinsic process of programmed cell death used by cells in all multicellular organisms, including humans, to control tissue homeostasis or to initiate their own death following malfunction or damage beyond repair.
  Developing precision medicines for B-cell leukaemias and lymphomas
  Dr S Macip, Prof M J S Dyer
Applications accepted all year round
In this project, we propose to look for novel therapies for B-cell leukaemias and lymphomas in a translational and mechanistic fashion.
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