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paediatric PhD Projects, Programmes & Scholarships
We have 15 paediatric PhD Projects, Programmes & Scholarships
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Identifying immune mechanisms in the CNS as targets for the treatment of paediatric Multiple Sclerosis (MS)
Paediatric MS accounts for 2.7-10.5% of the total MS population and can affect children of all ages. Paediatric MS is not curable and as such, is a lifelong debilitating disease that restricts the life quality of affected children for their entire life. Read more
Investigating the role of the microenvironment in paediatric and adult acute myeloid leukaemia
The incidence of acute myeloid leukaemia (AML) increases with age, and in childhood accounts for 20% of all leukaemia. The current overall survival rate in children is only 60-70%, and thereafter falls progressively with age to 5-15% in the elderly. Read more
Advanced manufacturing of paediatric formulations with poorly water soluble drugs
This project employs an advanced manufacturing technique, microwave-induced in situ amorphization, in combination with a wide range of characterization techniques to tackle the consistent stability issue of amorphous solid dispersions as a means of improving the dissolution performance of paediatric personalised formulations with poorly water soluble drugs. . Read more
Exploring the attitudes and scope of practice of UK optometrists in cases of paediatric high myopia
High myopia in childhood is a recognised association of ocular and systemic disease and may be the first clinical manifestation for some conditions (Marr et al., 2001). Read more
Developing evidence-based paediatric palliative care guidelines for Africa
Globally about 21.6 million children could benefit from palliative care, or services for young patients and families facing life-threatening illnesses. Read more
Utilising data linkage to estimate antimicrobial resistance burden in paediatric populations
The project will utilize data linkage techniques to link data from secondary care and primary care to evaluate antibiotic consumption and estimate antimicrobial resistance (AMR) burden in paediatric populations. Read more
Institute of Cancer Sciences
The Institute of Cancer Sciences is part of a national centre of excellence in the fight against cancer. We carry out a programme of world-class science directed at understanding the molecular changes that cause cancer. Read more
Mental health problems in pediatric cancer survivors
Paediatric cancer survivors are at increased risk of psychiatric illnesses including depression, anxiety and other mental health difficulties. Read more
The development of Rab27 inhibitors for treatment of cancer cell invasion and proliferation
Rab27 small GTPases regulate movement and exocytosis of secretory granules in cell types including; melanocytes (melanosomes), T lymphocytes (lytic granules), granulocytes (azurophilic granules) and mast cells [1]. Read more
Understanding the role of the hippo signalling pathway in ependymoma tumour biology
Ependymomas are tumours of the brain and spinal cord which affect paediatric and adult patients, representing the third most common malignant brain tumour in children. Read more
Mechanistic understanding of cancer drug induced cardiotoxicity using patient derived induced pluripotent stem cell (iPSC) derived cardiomyocytes
Background. Cardiovascular disease is the number one non-cancer cause of death in cancer survivors, attributable to side-effects of cancer medications routinely given to patients. Read more
Neurosciences
The primary objective of the Neuroscience doctoral degree programme is to prepare independent scientific and academic staff for the disciplines of General Neuroscience, Neurology, and Psychiatry. Read more
Understanding multiple and multi-dimensional transitions of young adults with life-limiting conditions and significant others
Change in health can trigger non-normative life transitions that can lead to multiple transitions for individuals and significant others. Read more
4-year PhD Studentship: Identifying children 10 or younger who are most at risk of abusive head trauma in the aftermath of the pandemic
Paediatric abusive head trauma (AHT) and traumatic brain injury (TBI) is when a child’s head is injured from being hit or shaken. Read more
Food Allergy in UK Adults
Many adults report adverse reactions to food (up to 30% in Europe), but IgE mediated food allergies are much less common (1-5%). The distinction is important as true food allergies can be life threatening whereas intolerances cause troublesome symptoms that can be debilitating but do not pose an immediate risk t life. Read more
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