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We have 19 patch clamp PhD Projects, Programmes & Scholarships

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patch clamp PhD Projects, Programmes & Scholarships

We have 19 patch clamp PhD Projects, Programmes & Scholarships

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THE CELLULAR ORIGIN OF SPATIAL DIFFERENCES FOR THE MATURATION OF LIGHT RESPONSES (ref: SF22/HLS/APP/HILGEN)

Vision is probably our most important sense. Vision starts in the retina, the light-sensitive tissue lining the back of the eye. It is a well-layered structure with synaptic (connections of neurons) and nuclear (cell bodies) layers. Read more

Funded PhD - Cannabinoids in the ticking network of the brainstem satiety centre

Life on Earth is subordinate to periodic alterations in the environment, with most notable changes seen from day to night. To react, anticipate, and adapt to these cyclic changes, living organisms evolved endogenous 24h timekeeping mechanisms named circadian clocks. Read more

MSC BY RESEARCH - Preserving t-tubule function in adult cardiac myocytes in short-term culture

Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more

Ion channel signalling in cancer cells

Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more

Develop single-cell biomechanical nanotools for novel cardiovascular mechanobiology and cancer immunotherapy

In view of the high complexity and dynamics of protein complexes that perform important physiological functions, it is difficult to visualise and characterise their kinetic and signaling processes on single living cells using traditional biochemical and biophysical techniques. Read more

Natural toxins and their synthetic analogues as tools to study ion channels and as potential drugs and pesticides

The project will use a combination of electrophysiological techniques such as voltage-clamp and patch-clamp with molecular biology and protein expression to understand how natural toxins and their synthetic analogues act on ion channels in the nervous system. Read more
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PhD studentship - Human iPSC-derived Sensory Neurons to Interrogate the Molecular Interplay between mTORC1 and Histamine Receptors in the Progression of Neuropathic Pain

Overview. Are you interested in exploring novel strategies to alleviate pain responses in patients with chronic pain? This PhD studentship will use stem cell-derived sensory neurons to understand the relationship between mTORC1 and histamine in chronic pain. Read more

Effects of insecticides on brain activity

Project Overview. Overview . This project is an exciting new collaboration between the University of Reading and Syngenta Group, to investigate the mammalian toxicity of insecticides and understand their effects on the brain. Read more

Combining laser and ultrasound based molecular delivery strategies for enhanced drug delivery

Overview. This project addresses the critical area of delivering therapeutics to the skin. If successful, the approach will have direct and positive consequences for the treatment of a range of skin diseases, but may also be viewed as a more generic means of drug delivery for treating a much wider range of disease. Read more

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