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patch clamp PhD Projects, Programmes & Scholarships
We have 12 patch clamp PhD Projects, Programmes & Scholarships
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Generating a computational model of dopaminergic networks and exploring the selective vulnerability of different neurons within this circuit to protein aggregates
This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more
Supramolecular Self-associating Amphiphiles (SSAs) – next generation weapons in the fight against antimicrobial resistance
One of the greatest threats against global human health is the rise of antimicrobial resistant bacterial infections, which are currently responsible for a greater number of global deaths then those currently attributed to HIV/AIDS or malaria. Read more
Stem Cell Exosomes - Important communicators with therapeutic potential on the dental pulp
The regenerative potential of mesenchymal stem cells has recently been attributed to exosomes, defined as extracellular vesicles of endocytic origin. Read more
Pathophysiology of red cell membrane permeability
Our project investigates how red cell membrane permeability is altered in pathophysiological states. Read more
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Investigation of novel molecular mechanisms for regulation of neuronal Calcium channels
Supervisor. Dr Ivan Kadurin. Funding. SBBS studentship. Deadline. 20th May 2022. The folllowing fully-funded PhD studentship is available in the School of Biological and Behavioural Sciences with an expected start date of Sept 2022. Read more
The role of neural stem cells and new neurons in regulating energy homeostasis
The project combines molecular biology and neuroscience to investigate the role of neural stem cells and new neurons in regulation of body weight. Read more
Natural toxins and their synthetic analogues as tools to study ion channels and as potential drugs and pesticides
The project will use a combination of electrophysiological techniques such as voltage-clamp and patch-clamp with molecular biology and protein expression to understand how natural toxins and their synthetic analogues act on ion channels in the nervous system. Read more
Mechanistic understanding of cancer drug induced cardiotoxicity using patient derived induced pluripotent stem cell (iPSC) derived cardiomyocytes
Background. Cardiovascular disease is the number one non-cancer cause of death in cancer survivors, attributable to side-effects of cancer medications routinely given to patients. Read more
Understanding why cardiovascular dysfunction is one of the leading causes of mortality in patients with Non-Alcoholic Fatty Liver disease (NAFLD)
Background. Liver disease accounts for 3.5% of all global deaths/year (~2 million people) and is the third leading cause of premature death in the UK with some of the highest hospitalisations in the country seen in areas of socioeconomic deprivation. Read more
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Astrocytes as regulators of neuronal autophagy in ageing brain
This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more
Combining laser and ultrasound based molecular delivery strategies for enhanced drug delivery
Overview. This project addresses the critical area of delivering therapeutics to the skin. If successful, the approach will have direct and positive consequences for the treatment of a range of skin diseases, but may also be viewed as a more generic means of drug delivery for treating a much wider range of disease. Read more
Deriving functional neurons from hIPSCs
Neuronal networks grown on petri dishes encode information as electrical activity. This activity is dictated by their underlying structural and functional connectivity. Read more
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