Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more
Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year. Read more
E. faecium is an important human pathogen which exhibits resistance to a range of antibiotics, and is implicated in a wide variety of device associated infections. Read more
Background and Timeliness. The world faces epidemics of antimicrobial-resistant (AMR) typhoid fever caused by Salmonella Typhi that underlies 12 million cases / 129 000 deaths each year. Read more
Antimicrobial resistance (AMR) is a significant concern in the battle against bacterial disease. Our understanding of resistance gene occurrence and spread as contributing to AMR is significant. Read more
In this age of increasing antimicrobial resistance, bacterial infections remain a major global health burden. During infection, bacterial pathogens deliver virulence proteins into the host cells. Read more
Applications are invited for a funded PhD position in the School of Chemistry at the University of Birmingham. The School of Chemistry is keen to achieve a gender and diversity balance across the School and welcomes applicants from all backgrounds. Read more
Understanding the mechanisms underlying patterns of SARS-CoV-2 transmission is important for informing strategic public health measures against respiratory pathogens more widely. Read more
Description. Zoonotic pathogens, such as COVID-19, reside in animal hosts before jumping species to infect humans. How diversity in host immune genes across species impact upon pathogen carriage are poorly understood. Read more
Fungal infections affect billions of people, including >1.5 million global deaths each year. Our failure to achieve cure against fungal infections results from the high levels of tolerance and resistance to antifungal drugs in clinical fungal isolates. Read more
The gut microbiome has a profound effect on health and disease of humans and colorectal cancer (CRC) is one such disease influenced by microorganisms. Read more
Natural Killer (NK) cells are immune cells that are critical for controlling intracellular pathogens, including viruses and intracellular bacteria (e.g. Read more
Bacterial pathogens respond rapidly to environmental change, in ways that can influence their growth, virulence, antimicrobial resistance and, therefore, infection outcomes. Read more
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