Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response.
Individuals vary tremendously in their propensity to transmit infections. Such host heterogeneity – most striking in the case of super-spreading and super-shedding individuals - makes it difficult to predict, manage, and curtail epidemics.
Understanding host responses to pathogen infection is critical for guiding the development of intervention strategies. Changes in gene expression are commonly observed upon infection, as exemplified by numerous transcriptomic studies.
This is an exciting PhD opportunity working with the University of Reading. It will focus on applying advanced sequencing technologies and population genomics to understand a globally challenging plant pathogen that currently threatens worldwide horticulture.