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pcr PhD Projects, Programs & Scholarships

We have 74 pcr PhD Projects, Programs & Scholarships

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  Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks
  Dr A Antonysunil
Applications accepted all year round
The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children.
  Mapping the circadian clock-dependent regulation of the secretory pathway
  Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round
The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
  Airway, Liver and Muscle Gene Transfer to Create Therapeutic Protein Factories: utilising experience of in vivo gene transfer and/or in vivo gene editing to understand and manipulate the factors required for effective expression and secretion of therapeutic proteins
  Dr S Hyde, Dr D Gill
Application Deadline: 26 July 2019
We are focusing on strategies to deliver therapeutics via in vivo delivery of gene transfer vectors to generate ectopic “protein factories” capable of secreting therapeutic proteins into both the lung lumen and the systemic circulation.
  Development of Gene Therapy and Gene Editing for Lung Disorders: the translation of new gene therapies to the clinic, including the development of new vectors, and evaluation in animal models of disease.
  Dr D Gill, Dr S Hyde
Application Deadline: 26 July 2019
The Gene Medicine Research Group is based in the John Radcliffe Hospital and is focused on the development of new gene therapeutics for lung diesases.
  British mosquito ecology: investigating the role of ecological traits, invasion status, and environmental factors in determining the distribution and seasonality of insect vectors in the UK
  Prof A Callaghan
Applications accepted all year round
Mosquito-borne diseases cause substantial mortality and morbidity worldwide and are changing in distribution and impact due to globalisation and environmental change.
  Interactions between melatonin and endogenous opioid peptide release
  Dr H Galley, Dr H M Wilson
Application Deadline: 30 April 2019
Overview. Control of pain remains a challenge for medicine. Melatonin, known for its role in circadian regulation, also has antioxidant and anti-inflammatory actions and has been suggested to have analgesic effects in a range of pain syndromes.
  Modulation of epigenetic phase variations in periodontal bacteria as a novel strategy for control of periodontal disease
  Dr K Hijazi, Dr G Cherukara
Application Deadline: 29 March 2019
Rationale and overall aim of the project. Periodontal disease (PD) is a major health issue in Scotland and worldwide with ever-increasing prevalence due to the increasing age of the population.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round
Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  Investigating metabolic changes in neurodegeneration
  Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round
This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
  Investigating neuronal patterning and development
  Dr F Mackenzie, Prof A Walker, Dr N Hill
Applications accepted all year round
This 3-year PhD will study molecular and cellular mechanisms of neuronal patterning and neural development using ex vivo/in vitro methods (mouse/human tissue/cells) and/or in vivo methods (invertebrates).
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