Mapping the circadian clock-dependent regulation of the secretory pathway
Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round
The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
Interactions between melatonin and endogenous opioid peptide release
Dr H Galley, Dr H M Wilson
Application Deadline:
30 April 2019
Overview. Control of pain remains a challenge for medicine. Melatonin, known for its role in circadian regulation, also has antioxidant and anti-inflammatory actions and has been suggested to have analgesic effects in a range of pain syndromes.
FGFR signalling in breast cancer
Dr A Chioni
Applications accepted all year round
Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
Investigating metabolic changes in neurodegeneration
Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round
This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
Investigating neuronal patterning and development
Dr F Mackenzie, Prof A Walker, Dr N Hill
Applications accepted all year round
This 3-year PhD will study molecular and cellular mechanisms of neuronal patterning and neural development using ex vivo/in vitro methods (mouse/human tissue/cells) and/or in vivo methods (invertebrates).
