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We have 40 peptide PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
peptide PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 40 peptide PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Enzyme-responsive peptide hydrogel as in situ forming long-acting drug delivery implants
One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more
Investigating the interactions of incretin hormone mimetics with hypothalamo-neurohypophysial system arginine vasopressin and oxytocin release
Our research focus over decades has been the osmoregulatory function of a special collection of neurones in a part of the brain called the hypothalamus. Read more
Structure based design of novel warheads for use in peptide-drug conjugates
Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Peptide-based nanoparticles for brain targeted gene delivery
Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more
Artificial Intelligence algorithms to predict aggregation and gel phenomena in peptide synthesis and isolation
Are you interested in helping to design the next generation of active molecules for applications in industry? Are you looking for a PhD position… Read more
Novel amphibian skin peptide-analogues for the treatment of type-2 diabetes
Research Group:
Biomedical Sciences
As part of ongoing programme into natural antidiabetic drug discovery; we isolated several novel insulin-releasing antihyperglycaemic agents from amphibian skin secretion for the treatment of type 2 diabetes. Read more
A novel strategy to combat Group B Streptococcus neonatal disease by targeting interkingdom interactions with fungus Candida albicans
Group B Streptococcus (GBS) is a major cause of infant death and morbidity worldwide, resulting in 147,000 stillbirths and infant deaths annually. Read more
Biological role of Stress Hormones
OVERVIEW. Our lab focuses on the biological roles of peptide hormones derived from pro-opiomelanocortin (POMC), a protein produced in the anterior pituitary gland. Read more
Building a novel, physiologically-relevant in vitro model of mesothelioma for improved predictivity of patient tumour response in drug screening studies
Malignant mesotheliomas are highly aggressive tumours arising from mesothelial-lined surfaces of the lungs and serosal spaces, predominantly associated with exposure to pathogenic asbestos fibres. Read more
Molecular genetic characterization of Drosophila reproductive behaviours for exploitation in insect population control
Research Group:
BBSRC MIBTP
Female reproductive behaviours in most insects profoundly change after mating leading to rejection of courting males and induction of egg laying. Read more
Control of nutrient metal availability during host-microbe interactions
BACKGROUND. Earth is home to a trillion of species of microbes. Some of these microbes associate with larger, more complex living organisms (hosts). Read more
Synthesis of Peptidomimetics Based on Functionalizable Freidinger Lactams
Despite mediating a plethora of vital biological processes in living organisms, peptides remain a challenging class of drug targets due to their poor cell penetration, proteolytic instability and unfavourable pharmacokinetics. Read more
SELF-FUNDING MSc BY RESEARCH PROJECT: Underlying mechanism of thrombogenesis in patients with severe coronavirus disease 19 (COVID-19)
Severe coronavirus disease 19 (COVID-19) is a disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Patients with COVID-19 are at significantly increased risk of thrombosis, which can be a challenge to manage and is associated with elevated mortality and morbidity. Read more
Leverhulme Trust Project Grant
The project is at the nexus of several rapidly emerging areas. mechanically interlocked molecules, macrocyclic peptides, and supramolecular chemistry in biology. Read more