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peptide PhD Projects, Programmes & Scholarships
We have 61 peptide PhD Projects, Programmes & Scholarships
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Peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention
HIV/AIDS is the leading cause of death in women of reproductive age worldwide. HIV and unintended pregnancies are prevalent in developing nations due to the lack of effective female contraceptive choice. Read more
Self-funded project: The role of peptide transporters in intrinsic resistance to beta-lactam antibiotics
Application accepted for either MSc by Research or PhD. The resistance of bacteria to antibiotics is a massive issue facing mankind, that threatens our ability to control infectious disease. Read more
Flexible Peptide Decorated Polyaminocarboxylate Ligands for Selective Extraction of Radiotherapeutic Metals for Targeted Alpha Cancer Therapy
Nuclear fission produces radioactive isotopes with decay products encompassing a large proportion of the Periodic Table. Many of these isotopes are considered as waste and are currently disposed of following separation. Read more
Development of peptide hydrogel as an anticancer drug carrier
Growth in nanotechnologies can now be exploited to enable engineering of new drug delivery systems for enhancing the entrapment of drugs in nano-sized structures with tailored physical properties to suit therapeutic need. Read more
Understanding how glucagon-like peptide-1 (GLP1) and gastric inhibitory polypeptide (GIP) receptors contribute to metabolism in complex tissues.
Our labs are focused on developing and using novel technologies to address challenging problems in cellular metabolism, with translational relevance for patients. Read more
Structure based design of novel warheads for use in peptide-drug conjugates
Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes. Read more
Neuropeptide Research – PhD Position at a World Class Institution
Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases. Read more
4-year PhD Studentship: Characterising the heterogeneity of type 1 diabetes across Bristol
Islet autoantibodies (iAabs) are established markers for type 1 diabetes (T1D) risk and classification. The European Reference Laboratory testing for a broad panel of iAabs (not all routinely available to the NHS) for a series of international studies, is based in Bristol. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Therapeutic targeting of chemokines in inflammation
Protein interactions underlie most biological processes but are challenging to target using small molecule drugs. Many protein interactions are mediated by short-linear-interacting motifs (SLiMs) that range from 3-12 amino acid residues (1, 2). Read more
What really makes a bacterial lipoprotein a real lipoprotein? Important implications for developing or improving lipoprotein-based vaccines
Bacterial lipoproteins have attracted much interest as vaccine candidates over recent years. The lipoprotein, Factor H binding protein, of Neisseria meningitidis for example is the sole antigen of Trumenba, the vaccine developed by Pfizer, and is a major component of the Bexsero vaccine developed by GSK. Read more
Biological role of Stress Hormones
OVERVIEW. Our lab focuses on the biological roles of peptide hormones derived from pro-opiomelanocortin (POMC), a protein produced in the anterior pituitary gland. Read more
Precise, peptide-directed loading of drugs onto therapeutic antibodies for targeted imaging and treatment of tumors.
The PhD project aims to develop a non-covalent technology for loading small molecules and therapeutic enzymes onto monoclonal antibodies thus addressing issues in preparations of antibody-drug conjugates, such as poor yields and non-specific conjugation of the drugs resulting in compromised immunoaffinity. Read more
Electronic switching of peptide self-assembly: new approaches for directing nanofabrication.
Research Group:
Intelligent Systems and Nanoscience
Biomolecular recognition is considered one of the most promising approaches for high-throughput nanofabrication. For example, the ability of proteins, peptides or DNA to assemble spontaneously into complex and well-defined 3D structures has been exploited for fabricating a range of nano-structured materials and devices. Read more
Molecular genetic characterization of Drosophila reproductive behaviours for exploitation in insect population control
Research Group:
BBSRC MIBTP
Female reproductive behaviours in most insects profoundly change after mating leading to rejection of courting males and induction of egg laying. Read more