Novel Computational Method Development for Shotgun Proteomics
Dr R Zhang, Dr D Lewandowska, Dr P Hemsley
4 January 2019
Background. Mass spectrometry (MS) based proteomics is the method of choice for characterizing proteins to understand biological functions and processes, elucidate signaling networks, discover disease biomarkers for human and identify key genes underlying important traits in plants.
Design, synthesis and evaluation of MMP-activated anti-cancer prodrugs
Institute of Cancer Therapeutics
Dr R Falconer, Prof P Loadman
Applications accepted all year round
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.