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We have 29 peptide chemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
peptide chemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 29 peptide chemistry PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Residue-selective late-stage functionalisation of peptides via electrosynthesis
A fully-funded 42-month PhD studentship in synthetic chemistry/peptide chemistry/electrosynthesis is available in the research group of Dr Nicholas Mitchell based in the School of Chemistry at the University of Nottingham (. Read more
PhD Studentship: Visible-light-mediated functionalisation of amino acids, peptides, and proteins
A PhD studentship funded by the Leverhulme Trust in synthetic chemistry/peptide chemistry/photochemistry is available in the research group of Dr Nicholas Mitchell based in the School of Chemistry, University of Nottingham (. Read more
Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2
Background. Coronaviruses (CoVs) are important human pathogens and SARS-CoV-2 is responsible for the current COVID-19 pandemic. Read more
Enzyme-responsive peptide hydrogel as in situ forming long-acting drug delivery implants
One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more
Development and Application of Enabling Methods for Drug Discovery
Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Thus, a major problem in life-sciences research is to understand and manipulate PPIs with molecular and temporal resolution. Read more
PhD in Chemistry - Synthesis of Fluorescent Amino Acids: Novel Tools for Biological Imaging
Candidates are invited to apply for a PhD position in the School of Chemistry, available to commence on 1st October 2023 in the Sutherland research group. Read more
Artificial Intelligence algorithms to predict aggregation and gel phenomena in peptide synthesis and isolation
Are you interested in helping to design the next generation of active molecules for applications in industry? Are you looking for a PhD position… Read more
New chemistry to enhance splice-switching oligonucleotides
Supervisory Team: Dr Ysobel Baker, Prof Diana Baralle and Prof Eugen Stulz. Project description. We are seeking a highly motivated individual to join our team as a fully funded PhD student developing new chemical modifications to improve the potency of splice-switching oligonucleotides. Read more
PhD in Chemistry: Computer simulation of metal-amyloid interaction and its role in plaque formation
Alzheimer’s disease is one of the greatest healthcare challenges facing 21st century society. AD is associated with formation of fibrils and plaques in brain tissue that impair proper functioning of neurons. Read more
Structure based design of novel warheads for use in peptide-drug conjugates
Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes. Read more
Development of peptide hydrogel as an anticancer drug carrier
Growth in nanotechnologies can now be exploited to enable engineering of new drug delivery systems for enhancing the entrapment of drugs in nano-sized structures with tailored physical properties to suit therapeutic need. Read more
Synthesis of Peptidomimetics Based on Functionalizable Freidinger Lactams
Despite mediating a plethora of vital biological processes in living organisms, peptides remain a challenging class of drug targets due to their poor cell penetration, proteolytic instability and unfavourable pharmacokinetics. Read more
Design and Engineering of Light-activated Enzymes for Chemicals Production
In this PhD studentship, we will pioneer generalized, rule-based design of photo-biocatalysts to open up new and high-energy catalytic reaction pathways. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Peptide-based nanoparticles for brain targeted gene delivery
Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more
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