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peptide design PhD Projects, Programmes & Scholarships
We have 19 peptide design PhD Projects, Programmes & Scholarships
Polypeptide/Surfactant Film Development for Biomedical Transfer Applications exploiting Novel Peptide Design
This project combines expertise in pharmacy and biotechnology to tune polypeptide/surfactant film properties through the design of novel peptides characterised using advanced physical characterisation techniques. Read more
Design of metallo coiled coil MRI contrast agents
This PhD project will develop a new class of MRI contrast agents. MRI is an essential tool for medical diagnosis. Contrast agents play a crucial role in improving the images obtained, and hence patient outcomes. Read more
Caging Circles: Engineering Medically Useful Cyclic Peptides into Artificial Programmable Protein Cages
About the Project. Advances in computational techniques now allow us to design artificial nanoscale structures from biological molecules such as proteins. Read more
Peptide-like hydrogels as long-acting injectable drug delivery platforms for the prevention of tuberculosis
Low to middle-income countries (LMIC) account for 95% of tuberculosis infections and deaths. Tuberculosis is currently the second highest infectious killer worldwide, after Covid-19, and is responsible for more deaths than HIV/AIDS. Read more
Peptide-like hydrogels as long-acting injectable drug delivery platforms for the prevention of malaria
There is an urgent need for new convenient drug delivery platforms to combat global health challenges in infectious disease, including malaria, and especially within low to middle-income countries (LMIC). Read more
Peptide-like hydrogels: A post-surgical sustained release drug delivery implant for the treatment of glioblastoma brain tumours
Glioblastoma is the most aggressive and malignant form of brain tumour with ~3,200 new cases annually within the UK and a median survival of 15 months. Read more
Self-Assembling Peptide Nanomaterials for Targeted Ocular Drug Delivery
Self-assembling peptide-based hydrogels (SAPH) are composed of short peptide sequences, typically consisting of 5 to 20 amino acids, which undergo spontaneous self-assembly into three-dimensional networks under physiological conditions. Read more
Peptide-like hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention
HIV in women, girls and mother-to-child transmission in pregnancy remain a significant source of new infections and the needs of females are inadequately addressed. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Protein hotspot mapping for protein-protein interaction studies and peptide ligand discovery
In this project, peptides, which match the sequence and structural diversity of proteins, will be used to probe proteins of biomedical interest. Read more
Developing anti-cancer drugs: Inhibiting Mortalin function to prevent cancer cell proliferation
These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more
Novel biocatalysts for amide and peptide bond synthesis
Background. The industrial transformation towards sustainable chemical manufacturing, that is essentialto meet net-zero goals in the future, emphasisesthe use of eco-friendly, bio-based resources, thus minimising the need for petrochemicals and reducing carbon emissions, waste and energy requirements. Read more
PhD in Chemistry - Designing and exploiting peptide nanotubes
Start date. 1st October 2025 . Peptide nanotubes are exciting biomaterials with unique structural and functional properties. Read more
Last chance to apply
Industrial CASE Studentship: Design, Synthesis and Biological Evaluation of Next-Generation Oligonucleotide Therapeutics
Background. Oligonucleotide (ON) therapeutics is an exciting clinically approved platform for the treatment of a range of diseases not readily accessible by small molecule drugs. Read more
New approaches to mass spectrometry analysis of cyclic and bicyclic peptides.
Title. New approaches to mass spectrometry analysis of cyclic and bicyclic peptides. Andrew Ray,1 Stephen Holman,2 Rachelle Black,1 Kamila Pacholarz,2 Joseph Gault3. Read more
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