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We have 16 peptide synthesis PhD Projects, Programmes & Scholarships

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peptide synthesis PhD Projects, Programmes & Scholarships

We have 16 peptide synthesis PhD Projects, Programmes & Scholarships

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Design and study of modified peptide foldamers

These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Investigating Neuropeptide Signalling From Synthesis to Survival

Project Overview. Neuropeptides, comprising of short amino acid chains, are potent bioactive molecules with extensive neuromodulatory functions and are predominantly expressed within the central nervous system. Read more

Synthesis of Peptidomimetics Based on Functionalizable Freidinger Lactams

Despite mediating a plethora of vital biological processes in living organisms, peptides remain a challenging class of drug targets due to their poor cell penetration, proteolytic instability and unfavourable pharmacokinetics. Read more

Artificial cyclic peptide library for novel antimicrobial resistance therapeutics and targeted delivery

Supervisory Team: Dr Afaf El-Sagheer and Dr Sandra Wilks. PhD Supervisor. Afaf El-Sagheer. Project description. A fully-funded 4 year PhD studentship is available for drug discovery research on Antimicrobial Resistance (AMR) at the University of Southampton. Read more

Unravelling the Intricacies of Stress Hormone Regulation

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Development of PET Radiotracers for Neuroinflammation

Our aim is to develop novel Positron Emission Tomography (PET) radiotracers for imaging the brain. PET is a non-invasive molecular imaging technique which enables visualization and quantification of various biological targets in vivo (e.g., receptor, enzyme). Read more

A new twist on catalysis: folded oligomers with organometallic termini

A key feature of biological systems is the storage and transmission of information across multi-nanometre distances, which maintains the complex chemical networks and functions within cells. Read more

Development and Application of Enabling Methods for Drug Discovery

Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Thus, a major problem in life-sciences research is to understand and manipulate PPIs with molecular and temporal resolution. Read more

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