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peptides PhD Projects, Programmes & Scholarships

We have 45 peptides PhD Projects, Programmes & Scholarships

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We have 45 peptides PhD Projects, Programmes & Scholarships

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Therapeutic targeting of chemokines in inflammation

Protein interactions underlie most biological processes but are challenging to target using small molecule drugs. Many protein interactions are mediated by short-linear-interacting motifs (SLiMs) that range from 3-12 amino acid residues (1, 2). Read more

Computer simulation of metal-amyloid interaction and its role in plaque formation

Alzheimer’s disease is one of the greatest healthcare challenges facing 21st century society. AD is associated with formation of fibrils and plaques in brain tissue that impair proper functioning of neurons. Read more

Metal-Mediated Modification of Peptides and Proteins

We have shown that robust organometallic complexes can selectively functionalise natural amino acids by targeting nucleophilic residues such as cysteine to provide peptides and proteins with unique structures [1]. Read more

Microneedle delivery of non-ribosomal antimicrobial peptides to treat multidrug-resistant Gram-negative infections

The increasing prevalence of infections caused by multidrug-resistant (MDR) bacteria is a major global concern, with global deaths due to antimicrobrial resistance expected to hit ten million per year by 2050. Read more

Protease-resistant antimicrobial peptides to target bacterial and fungal pathogens

Antimicrobial resistance is quickly becoming a serious global health problem. The emergence of multidrug-resistant microbial strains combined with the drying up of the antibiotic pipeline in the pharmaceutical industry has significantly worsened the situation in recent years. Read more

A non-invasive robotic capsule for oral delivery of peptides and proteins

While significant advances have been made in administrating these biologics through the parental routes, delivering these molecules orally remains a major challenge for pharmaceutical industry. Read more

Chemo-enzymatic Synthesis and Potential Applications of Novel antimicrobial peptides

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses. Read more

Development of peptide hydrogel as an anticancer drug carrier

Growth in nanotechnologies can now be exploited to enable engineering of new drug delivery systems for enhancing the entrapment of drugs in nano-sized structures with tailored physical properties to suit therapeutic need. Read more

Design and characterisations of novel antimicrobial biomaterials

Self-assembled nanobiomaterials are becoming an important research theme due to their potential in infection control and wound care, gene and cell delivery, biodevices and tissue regeneration. Read more

Biological role of Stress Hormones

OVERVIEW. Our lab focuses on the biological roles of peptide hormones derived from pro-opiomelanocortin (POMC), a protein produced in the anterior pituitary gland. Read more

Peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention

HIV/AIDS is the leading cause of death in women of reproductive age worldwide. HIV and unintended pregnancies are prevalent in developing nations due to the lack of effective female contraceptive choice. Read more

Nanostructured Self-Assembly of Bio-Derived and Bio-Inspired Lipid-Based Amphiphiles: Synthesis

This exciting research project is associated with an EPSRC Fellowship award to Prof Hamley. This is a 4-year project which also involves two postdoctoral researchers and another PhD studentship. Read more

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