We have 30 peptides PhD Projects, Programmes & Scholarships

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peptides PhD Projects, Programmes & Scholarships

We have 30 peptides PhD Projects, Programmes & Scholarships

PhD in Chemistry: Computer simulation of metal-amyloid interaction and its role in plaque formation

Alzheimer’s disease is one of the greatest healthcare challenges facing 21st century society. AD is associated with formation of fibrils and plaques in brain tissue that impair proper functioning of neurons. Read more

Self funded MSc by research or PhD in Biology: Paratransgenesis for leishmania

Lead supervisor: Dr D Jeffares (Dept of Biology). Co-Supervisor: Dr Sean Meaden and Dr Paul Fogg (Dept of Biology). The student will be registered with the Department of Biology. Read more

Unravelling the Intricacies of Stress Hormone Regulation

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

A novel peptide based approach to inhibit growth of antimicrobial resistant pathogens

Project description. Antimicrobial resistance (AMR) is one of the biggest global challenges to human health in the 21st century, with the worst-case scenario development of a raft of incurable infections, especially Hospital Gram negative pathogens. Read more

An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

Supervisory Team: Prof Ali Tavassoli . Project Description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. . Read more

Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Computational and machine learning driven development of new polysialyltransferase (ST8SiaII) inhibitors against metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid (polySia) is a carbohydrate polymer important for embryonic development. PolySia is absent in healthy adult tissues whereas overexpressed in several tumours. Read more

Engineering Ice-Binding Proteins

Ice-binding proteins are produced by extremophiles to help them survive in the worlds coldest places. They have many potential applications, from the storage of cells/tissue to transport infrastructure. Read more

Development and Application of Enabling Methods for Drug Discovery

Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Thus, a major problem in life-sciences research is to understand and manipulate PPIs with molecular and temporal resolution. Read more

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