Cationic antimicrobial peptides as anticancer agents
Dr R Green, Prof R A Frazier
Applications accepted all year round
Cationic peptides are widespread in nature where they play a key role in host defense within plants and animals. The mechanism by which these peptides interact with cell membranes potentially leads to these being less prone to antimicrobial resistance than conventional antibiotics.
(BBSRC DTP) Inhibition of SR protein kinase 1 with designer peptides
Dr A Golovanov, Dr A Almond
31 January 2019
This PhD project addresses BBSRC’s ENWW in that the student will be trained in. Biophysical techniques - ITC, SPR, CD; Structural biology techniques - solution state NMR and X-ray crystallography; Computational techniques - molecular dynamics simulations and computer modelling and analysis.
A dynamic biomaterial-ligand tethering strategy for tissue engineering
Dr C Spicer, Prof D K Smith
9 January 2019
Biomaterials that can trigger the repair of damaged tissues have the potential to revolutionise the way we treat disease. Materials that can present cells and tissues with powerful biochemical signals, through attached peptides, proteins, and carbohydrates, are particularly effective at controlling regeneration.