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phagocytosis PhD Projects, Programs & Scholarships

We have 10 phagocytosis PhD Projects, Programs & Scholarships

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  MRC DiMeN Doctoral Training Partnership: How do superbugs hide from the host? Understanding the mechanisms of innate immune evasion in the opportunistic pathogen Enterococcus faecalis
  Dr S Mesnage, Dr P Elks
Application Deadline: 21 January 2019
All enterococci produce a surface polysaccharide called the enterococcal polysaccharide antigen (EPA) that plays a key role during pathogenesis (Mistou et al., 2016).
  Developing a three-dimensional research model of neutrophil-mediated tissue destruction during inflammation
  Dr J Hirschfeld, Prof I L C Chapple, Dr M Grant
Applications accepted all year round
Background. The proposed research has the goal to develop a novel 3D model to measure and visualise tissue destruction mediated by migrating neutrophils in vitro.
  Non-canonical signalling mechanisms in phagosome maturation
  Prof C E Eyers
Application Deadline: 11 January 2019
Phagosomes are intracellular vesicles that are formed by phagocytosing particles such as bacteria or apoptotic cells by specialised immune cells.
  Macrophage biology in inflammation
  Prof D R Greaves
Application Deadline: 11 January 2019
Work in the Greaves Laboratory aims to understand how macrophage differentiation contributes to both inflammation initiation and tissue repair.
  MRC DiMeN Doctoral Training Partnership: Determination of how killer pathogenic fungi evade human innate immune defences
  Prof J Quinn, Dr S Johnston
Application Deadline: 21 January 2019
More people die from fungal infections than from malaria, tuberculosis, or ‘superbugs’ such as MRSA. Candida species are an important group of human fungal pathogens causing over 400,000 life threatening infections per year.
  Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam
  Dr M Soller
Application Deadline: 20 January 2019
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response.
  Cross-presentation of exogenous ROP proteins by antigen presenting cells to MHC class I and class II pathways
  Dr S Jiang, Dr N Burgess-Brown
Application Deadline: 11 January 2019
Immunotherapy including therapeutic vaccines provides great hope for cancer treatment. Understanding the mechanisms of antigen presentation is helpful for optimal design of an immunotherapy.
  MRC DiMeN Doctoral Training Partnership: Optogenetic programming of inflammation - in vivo Opto-GPCR approaches in neutrophils
  Prof S Renshaw, Prof A Condliffe
Application Deadline: 21 January 2019
Diseases of inflammation contribute to the biggest health problems of the 21st century. Mutli-morbidity, the coincidence of multiple pathologies, is driven by processes such as inflammation and by inflammatory cells like neutrophils.
  MRC DiMeN Doctoral Training Partnership: Boosting immunity in chronic lung disease and antimicrobial resistant infection via the IL-33-ST2 axis
  Dr S Johnston, Prof S Renshaw, Dr A Humbles
Application Deadline: 21 January 2019
Macrophages are effector cells that directly kill microbes and regulatory cells that coordinate the wider immune response. Due to the complex nature of macrophage function, how their different roles are integrated during infection and inflammation is still poorly understood.
  Investigating the long-term effects of chronic radiation exposure on cellular mechanisms
  Dr J Lim, Prof D Copplestone, Prof N Beresford
Application Deadline: 14 December 2018
Despite decades of research into radiation effects on wildlife, controversy remains concerning the dose rate at which significant impacts occur for different types of organisms1.
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