MALDI. mass spectrometry has been a cornerstone of modern biological mass. spectrometry, enabling the soft ionization, analysis and characterisation of. Read more
This project aims to develop transdermal microneedle formulations for delivering biologic drugs over several weeks or months. Biologics (e.g. Read more
Soft tissue reconstruction is emerging as an important strategy to repair and replace diseased or damaged tissue that has been compromised due to tumour removal, injury, trauma, ageing, etc. Read more
The reduction of emission from pharmaceutical tablet manufacturing is urgent and challenging. Rapid identification and quantification of emission sources is an important milestone to set reduction targets and implement corresponding reduction measures. Read more
Tablet is a complex pharmaceutical product in oral dosage form which contains blends of active pharmaceutical ingredients (APIs) and excipients. Read more
Some brain cancers cannot be surgically removed, and many potent therapeutics cannot reach the tumour site. This project aims to overcome these hurdles by utilizing a recently developed multifunctional nanoparticle drug delivery system that can be injected directly into tumours. Read more
Ultrafast 2D-IR spectroscopy is a new variant of Infrared spectroscopy which offers a unique analytical method for characterizing complex biomolecular samples. Read more
There is much interest in 3D heterocyclic scaffolds for medicinal chemistry. Within fragment-based drug discovery, we are developing a synthetic platform to enable the elaboration of 2D fragments into 3D lead compounds, addressing limitations highlighted by industry. Read more
Background. Neurological diseases are currently the 2nd leading cause of death, and the leading cause of disability adjusted life years (DALY) worldwide1. Read more
Particle processing is widely used in chemical and pharmaceutical manufacturing industries. In this context, particle attributes influence processability and are key to the optimisation of product quality. Read more
While traditional, small molecule drugs continue to play a significant role due to their oral bioavailability, they also suffer from lower selectivity, frequently accompanied with side-effects. Read more
This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more
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