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pharmaceutical sciences PhD Projects, Programs & Scholarships

We have 87 pharmaceutical sciences PhD Projects, Programs & Scholarships

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We have 87 pharmaceutical sciences PhD Projects, Programs & Scholarships

Development of lipid-based nanocarriers using melt extrusion for oral peptide delivery

Peptide-based drugs are an important class of medicine used for the treatment of many relevant disorders. However, their delicate physicochemical characteristics, poor membrane permeability and harsh conditions along the gastro-intestinal tract pose hurdles in providing effective therapy. Read more

Microfluidics in Nanomedicine

Progress in drug design has led to the development of new molecules. However, the limited ability to selectively deliver these molecules at well-defined dosing regimens remains a significant challenge. Read more

SMART Nanocarriers for Cancer

An important limitation in the treatment of cancer with therapeutics is the inability to achieve therapeutically effective local drug concentrations avoiding healthy tissue damage. Read more

Development of precisely engineered nanocrystals for selective tissue targeting

A considerable number of infectious diseases affect the lymphatic system and are difficult to treat because the pathogens that cause them can form reservoirs in such tissues, where current treatments can not provide sufficient concentrations of the active to eradicate these microorganisms. Read more

To investigate the pharmacological responses of senolytics in cancer

Chemotherapy causes cancer cells to become senescent and increased resistance to standard-of-care cancer therapies. Senescent cells stop dividing but remain metabolically active. Read more

High-throughput discovery of novel antibiotics using synthetic microbiology

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year. Read more

Development of long-acting drug delivery platform (LADDP) to treat chronic disorders

LADDPs can offer significant advantages over traditional delivery systems by reducing the frequency of drug administration such as in the treatment of cancer, schizophrenia and pain. Read more

New tools for the diagnosis of pathogenic bacterial infections

Antibiotics are no longer as effective as they were at the start of this century. This is largely due to evolutionary changes within bacterial known as antimicrobial resistance (AMR), which is promoted by inappropriate use of antibiotics. Read more

Anaemia of Chronic Kidney Disease: An All-Wales primary and secondary care prevalence and incidence study

Aim. The project will investigate the prevalence of ACKD in Wales across primary and secondary care. It will follow patients with CKD G3-5 to explore the association between ACKD and hospitalisation and mortality. Read more

Molecular mechanisms underlying Parkinson's disease

There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more

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