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pharmacokinetic PhD Projects, Programmes & Scholarships
We have 9 pharmacokinetic PhD Projects, Programmes & Scholarships
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Treatment of infections caused by multidrug-resistant Gram-negative infections through microneedle delivery of antimicrobial peptides
Antimicrobial resistance (AMR) is a critical threat to human health and novel antibiotics and treatments are desperately needed to prevent a future pandemic. Read more
Mechanistic models for protein binding and transport in organ impairment
When evaluating impact of disease on drug response, measurement of total drug concentration is typically used as surrogate for free drug concentration and pharmacological effect. Read more
Microneedle delivery of non-ribosomal antimicrobial peptides to treat multidrug-resistant Gram-negative infections
The increasing prevalence of infections caused by multidrug-resistant (MDR) bacteria is a major global concern, with global deaths due to antimicrobrial resistance expected to hit ten million per year by 2050. Read more
New Hybrid C-H Functionalisation and Photochemical Strategies for Chemical Synthesis
This project aims to develop new synthetic methods that deliver increased efficiency and precision in the synthesis of spirocyclic sp3-rich molecules. Read more
Mathematical models for preclinical drug trials: small molecule drugs and antibody drug conjugates
Preclinical evaluation of drug efficacy plays a fundamental role in the development of cancer treatments, with the aim being to evaluate drug action and anti-tumour effect. Read more
Self Funded PhD Project: Studies on the Design, Synthesis and Biological Evaluation of a Novel Bioactive Indane Scaffold
A wide range of bioactive indane based scaffolds are employed clinically as treatment of many disease states, including inflammatory [1], cancer [2] and neurological conditions [3] and also in the treatment of HIV [4]. Read more
Peptide hydrogels as a long-acting multipurpose drug delivery platform for combined contraception and HIV prevention
HIV/AIDS is the leading cause of death in women of reproductive age worldwide. HIV and unintended pregnancies are prevalent in developing nations due to the lack of effective female contraceptive choice. Read more
Development of antibody-drug conjugates (ADCs) for oncology indications
Research Group:
Institute of Cancer Therapeutics
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more
Investigation into the in-vitro lung deposition of liposomal formulations of the dual fixed-dose combination inhaler
Research Group:
Medicines Development and Pharmaceutical Sciences
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are diseases associated with the airflow in the lungs (WHO, 2013). Inhalation is the most effective route of administration for treating asthma and COPD (Labiris and Dolovich, 2003). Read more
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