Design, synthesis and evaluation of MMP-activated anti-cancer prodrugs
Institute of Cancer Therapeutics
Dr R Falconer, Prof P Loadman
Applications accepted all year round
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.
Prediction of nanoparticle stability using advanced physico-chemical techniques
Prof J Lawrence, Dr A Pluen, Dr R Curtis
31 January 2019
Lipid nanoparticles (LNPs), in their various forms - including solid lipid nanoparticles, nanostructured lipid carriers, lipid drug conjugate and polymer-lipid hybrid nanoparticles - have attracted considerable interest as delivery vehicles for a range of therapeutic candidates.