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  Dynamic prediction modelling in Parkinson’s Disease
  Dr D McLernon, Dr A Macleod
Application Deadline: 22 March 2019
1. Background to the project. Parkinson’s disease (PD) is a progressive, disabling, neurodegenerative disorder which is common in the elderly.
  Individual participant data meta-analysis of randomised controlled trials comparing elective freezing of embryos followed by thawed frozen embryo transfer versus fresh embryo transfer in in-vitro fertilisation
  Dr D McLernon, Dr A Maheshwari
Application Deadline: 22 March 2019
Background to the project. During in-vitro fertilisation (IVF), women are treated with hormone injections so that their ovaries can produce multiple eggs.
  Psoriatric arthritis (PsA)
  Dr G Jones, Dr R Hollick
Application Deadline: 22 March 2019
Psoriatic arthritis (PsA) affects around 120,000 people in the UK. In addition to psoriasis (skin disease) patients can have inflamed, stiff and painful joints which, in severe cases, can become permanently deformed or damaged, and may require surgery.
  A 3D in vitro model of wound healing incorporating skin, nerves and immune cells
  Dr A M Rajnicek, Dr H M Wilson
Application Deadline: 29 March 2019
Diabetes, paralysis, being bed ridden and other conditions can result in chronic wounds that fail to heal, with significant personal consequences for patients and an annual cost of £4.5-5.1 billion annually (Guest et al., 2015) to the National Health Service.
  A novel approach to manage neuroinflammation-driven central neuropathic pain after spinal cord injury
  Dr W Huang, Prof C McCaig, Prof R Pertwee
Application Deadline: 29 March 2019
Worldwide, spinal cord injury (SCI) affects around 2.5 million people with estimated additional 500,000 new cases annually. About 50% of SCI patients suffer from central neuropathic pain (CNP), which has a major impact on daily functioning, affect rehabilitation, and often leads to depressive and suicidal states.
  Analysis of intracellular sCTLA-4 and its contribution to intrinsic cell regulation
  Dr F J Ward, Dr R Abu Eid
Application Deadline: 29 March 2019
Cancer immunotherapy is among the most important recent developments in cancer treatment. Despite its impressive successes, however, the response in some patients is often limited and short lived.
  Development of ex vivo tissue culture models for developing next-generation biomaterial scaffolds for acellular regenerative medicine.
  Prof I Gibson, Prof N Vargesson
Application Deadline: 29 March 2019
Bone repair and regeneration can be influenced by various guidance cues, including pharmacological cues, hypoxia environment and chemical cues released from scaffolds [1-3].
  Do rural-dwellers experience cancer symptoms differently? A mixed methods PhD project using the USEFUL (a community-based cohort assessing prevalence and response to potential cancer symptoms)
  Prof P Murchie, Dr J Allan, Dr S Fielding
Application Deadline: 29 March 2019
1. Background to the project. Scottish people living further from key healthcare facilities have less chance of prompt cancer diagnosis and poorer cancer survival than those living closer-by[1].
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