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platelets PhD Projects, Programmes & Scholarships
We have 15 platelets PhD Projects, Programmes & Scholarships
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Platelet-cell interactions: Platelets beyond thrombosis and haemostasis
Platelets play a key role in the prevention of bleeding following blood vessel damage. In addition to this important role, platelets also impact the… Read more
Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases
"Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more
Platelets in health, ageing and disease: new diagnostics and treatments
Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
The Role of B7-H1 in Platelet Activation and Immunothrombosis
A British Heart Foundation funded PhD studentship position to work on the highly exciting role of B7-H1 in platelet activation and immunothrombosis is now available. . Read more
Using CRISPR in iPS cells to modify platelet function
Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus. Read more
The regulation of platelet function - towards new strategies to prevent thrombosis
Project Overview. Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding. Read more
4-year PhD Studentship: Sticky but not sweet: deciphering how Streptococcus bacteria drive clot formation and heart disease
Heart disease is the leading cause of mortality in the developed world. Viridans group Streptococcus bacteria (VGS) are a major cause of infective endocarditis (IE), a severe form of heart disease characterised by clot formation on heart valves[1,2]. Read more
Understanding the molecular mechanisms of thrombosis and haemostasis
Project Overview: . The risk of heart attack or stroke is elevated in obesity and in people with metabolic disorders such as diabetes. Read more
Systems level analysis of platelet signalling
We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation. Read more
PhD Studentship in Molecular Dynamics Modelling of Bone Tissue
Applications are invited for a research studentship in the field of mechanics of bone across the scales, leading to the award of a PhD degree. Read more
Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more
Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more
Investigating by Single-cell Multi-omics of Blood Cell Development
Blood Cells are used daily in medical and cancer treatments such as transfusions, bone marrow / haematopoietic stem cell (HSCs) transplantations, and immunotherapies. … Read more
How has Covid-19 changed blood donation decisions and motivations and what are the long-term implications?
Unlike other NHS services, blood donation did not pause during the covid-19 lockdown, but instead leaving your home to donate blood was considered 'essential travel'. Read more
Extracellular vesicles in health and disease
Endothelial dysfunction (ED) is associated with classical and emerging risk factors of cardiovascular disease (CVD), correlates with disease progression and is an independent predictor of the risk of future cardiovascular events. Read more
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