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pluripotent PhD Projects, Programmes & Scholarships

We have 28 pluripotent PhD Projects, Programmes & Scholarships

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We have 28 pluripotent PhD Projects, Programmes & Scholarships

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The Roadmap of Human Pluripotency, Living Systems Institute – PhD

In the early mammalian embryo a group of cells form that have the special property of pluripotency. Pluripotency is the developmental potential of a cell to generate the founder lineages of the embryo. Read more

MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. . Read more

Genetic and biochemical evaluation of a Gaucher disease patient utilising induced pluripotent stem cell (IPSC) technologies

We are looking for a talented and motivated recent graduate in Neuroscience, Biosciences or related discipline to engage in an exciting new project at Manchester Metropolitan University in collaboration with the Inherited Metabolic Diseases clinical team at the . Read more

An omics approach to understand and treat KMT2C-related neurodevelopmental disorder using induced pluripotent stem cells and CRISPR-Cas9

Background. We recently identified a novel human syndrome caused by mutations in a gene called KMT2C1. Patients with this condition predominantly have developmental delay and intellectual disability indicating the important function of this gene in brain’s normal development and function. Read more

Characterisation and treatment of patient iPSC-derived retinal organoids as an in vitro model of inherited retinal disease

Commercial partner: . Newcells Biotech Ltd. , Newcastle upon Tyne. Induced pluripotent stem cell (iPSC) derived 3D retinal organoids (ROs) mimic the architecture of the mammalian retina and can therefore be used as a physiologically relevant in vitro model. Read more

BBSRC White Rose DTP Studentship - Investigating functional conservation of Specialized ribosomes in eukaryotes

Ribosomes are the ancient cellular machines that perform protein synthesis. Although long considered uniform in both composition and function, recent findings have shown ribosomes to be far more heterogeneous than originally thought. Read more

Mechanisms of gene regulation shared between human development and neurodegeneration

Applications are invited for a research studentship leading to the award of a PhD degree, under the supervision of Dr. Marco Trizzino, to investigate mechanisms of gene regulation shared between human development and neurodegeneration. Read more

PhD Studentship in Psychological Medicine and Clinical Neurosciences

Project Title. Untangling neurodegeneration and ageing components of neuroinflammatory disorders. Summary. Numerous genome-wide association studies (GWAS) show a strong, but poorly understood neuroinflammatory component to most neurological diseases. Read more

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