This project will generate human retinal ganglion cells (RGCs) for therapeutic testing. We will replace mouse tissue with human RGCs differentiated from patient-derived induced pluripotent stem cells (hiPSCs) from dominant optic atrophy caused by mutation in the OPA1 gene and from normal controls. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Background. We recently identified a novel human syndrome caused by mutations in a gene called KMT2C1. Patients with this condition predominantly have developmental delay and intellectual disability indicating the important function of this gene in brain’s normal development and function. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Rationale. A heat shock response (HSR) or stress response (SR) is generated in all cells following expose to elevated temperatures and various other stressors. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells) are pluripotent and thus hold great promise in regenerative medicine, studying disease mechanisms and drug discovery. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Neurovascular dysfunction is a central process in the pathogenesis of Alzheimer’s disease and other dementias. In the brain, vascular and neuronal structures are tightly integrated forming the multicellular neurovascular unit comprising endothelial cells, pericytes, astrocytes, microglia and neurons. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Rationale. Parkinson’s is a neurodegenerative disorder that is characterised by the loss of dopamine neurons in the substantia nigra, leading to impairment of the motor system and other non-motor symptoms such as loss of smell, cognitive and sleep disorders. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Applications are invited for a four year Postgraduate studentship, supported by the Midlands Integrative Biosciences Training Partnership (MIBTP) and Biotechnology and Biological Sciences Research Council (BBSRC), to be undertaken in the. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This research project has funding attached. It is only available to UK citizens or those who have been resident in the UK for a period of 3 years or more. Some projects, which are funded by charities or by the universities themselves may have more stringent restrictions.
This project is available through the MIBTP programme.. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. For further details please visit the MIBTP website - . Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This research project has funding attached. It is only available to UK citizens or those who have been resident in the UK for a period of 3 years or more. Some projects, which are funded by charities or by the universities themselves may have more stringent restrictions.
The Porcher lab investigates how Haematopoietic Stem Cells (HSCs, the cells with self-renewal and multilineage potentialities that give rise to the entire blood system) are produced during embryonic development. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
The Porcher lab investigates how Haematopoietic Stem Cells (HSCs, the cells with self-renewal and multilineage potentialities that give rise to the entire blood system) are produced during embryonic development. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Abstract. Cardiac arrhythmias are a major cause of morbidity and mortality. Arrhythmias occur when the normal flow of electricity in the heart becomes disordered. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.
Application deadline. 3rd March. Interviews to be held. 31 March 2021. Dysregulation of the blood-brain barrier (BBB) is an early and critical event in the pathogenesis of neurovascular diseases, such as Alzheimer’s disease, vascular dementia and stroke. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Application deadline. 3rd March. Interviews to be held. 31 March 2021. Dysregulation of the blood-brain barrier (BBB) is an early and critical event in the pathogenesis of neurovascular diseases, such as Alzheimer’s disease, vascular dementia and stroke. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Application deadline. 3rd March. Articular cartilage (AC) defects are one of the major causes of immobility and poor quality of life for millions of individuals worldwide. Read more
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.