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polymerase PhD Projects, Programs & Scholarships

We have 11 polymerase PhD Projects, Programs & Scholarships

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  Statistical physics of DNA replication
  Dr A Moura, Prof C Romano
Applications accepted all year round
The goal of this project is to apply statistical physics and probability theory to the problem of DNA replication in living cells.
  Why do some DNA sequences poison cells?
  Research Group: BBSRC MIBTP
  Dr D Grainger
Applications accepted all year round
Life on our planet is permitted by an ancient set of instructions encoded by DNA. Consequently, the observation that a cell can be poisoned by its own DNA is completely counterintuitive.
  Structural mechanism of signal-dependent gene transcription
  Prof D Panne, Dr A Revyakin
Application Deadline: 5 May 2019
The control of gene transcription is one of the main regulatory steps for cellular gene regulation.
  Defining the ‘molecular signature’ of PARP inhibitor sensitivity in blood cancers
  Dr T Gaymes
Applications accepted all year round
Despite significant advances in the understanding of the biology of blood cancers, identification of the most effective and safe form of treatment continues to present a formidable challenge to clinicians.
  Characterize the role of Treacle (TCOF1) in AKT-regulated ribosome biogenesis
  Prof R. Pearson, Dr J Kang
Applications accepted all year round
Ribosomes are essential for cell growth and proliferation, and their biogenesis requires exquisite regulation.
  MASTERS BY RESEARCH PROJECT: Maturing stem cell-derived cardiomyocytes to provide improved models of arrhythmia
  Dr S Harmer, Prof J C Hancox
Applications accepted all year round
Start 23 September 2019. This MSc by Research is a laboratory-based project which offers the exciting opportunity to spend 1 year in one of our State-of-the-Art laboratories (plus 1 year thesis writing) at the University of Bristol and experience life as a researcher.
  Understanding the role of HoxA9 in chemotherapy resistance of Acute Myeloid Leukaemia (AML)
  Dr M Esposito
Applications accepted all year round
Acute Myeloid Leukaemia (AML) is a rare but yet deadly form of blood cancer. Genome-wide expression arrays and RNA sequencing have contributed to unravelling the leukaemia signature genes.
  Engineering E. coli as a cell factory for biotechnology
  Dr J Green
Applications accepted all year round
The model bacterium Escherichia coli is metabolically versatile with ability to adapt to ever changing environmental conditions by reprogramming gene expression.
  Self-association of the Alzheimer’s peptide Aβ on membrane surfaces
  Prof M P Williamson
Applications accepted all year round
Alzheimer’s disease is a neurodegenerative disease that is particularly common amongst the elderly. It accounts for about 65% of all cases of dementia, and affects about 6% of people over 65, rising to 50% of people over 85.
  Structural biology of the intrinsically disordered protein SH2B1
  Prof M P Williamson
Applications accepted all year round
Signalling between the outside of the cell and the inside uses a complicated network of interacting systems. One common signalling mechanism uses receptor tyrosine kinases.
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