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  Optimising Product Quality of In Vitro Transcribed mRNA Therapeutics
  Dr A Brown
Application Deadline: 25 February 2019
A fully funded BBSRC/MedImmune PhD studentship is available in the Department of Chemical and Biological Engineering at the University of Sheffield, starting in October 2019.
  Toward a theory of evidence-based product design - Investigating the potentials of big data and Artificial Intelligence for the domain of design
  Dr J Lamb, Dr W Cooper
Application Deadline: 29 March 2019
Big data is here to stay. It is transforming the way businesses operate. Advances in social media, Cloud Computing, Internet of Things have had a substantial influence on the amount of data that is available to the businesses today.
  Linking Process and Product Models for Wet Granulation: Modelling Agglomerate Structure
  Dr R Smith, Prof J Litster
Application Deadline: 23 January 2019
Wet granulation is a method of particle size enlargement used across a large range of industries. In particular, it is an integral operation in the pharmaceutical, food, minerals processing, consumer products and agrichemical industries.
  Efficient simulation of the effect of mixing and flow condition on product crystal qualities in a continuous crystallizer using coupled CFD-PBE approach
  Dr A Majumder, Dr J Derksen
Applications accepted all year round
The majority of the active pharmaceutical ingredients (APIs) used in the pharmaceutical industries are crystals of organic molecules.
  Intelligent product-service systems in smart cities: Advancing co-design and systems engineering practices
  Dr M King
Application Deadline: 28 January 2019
Reference number. WS12. Start date of studentship. 1st October 2019. Closing date of advert. 28th January 2019. Interview date. TBC.
  4 year Engineering Doctorate (EngD): Intelligent Machining to digitize the whole product lifecycle using advanced modelling and virtual reality tools (Sponsors: University of Sheffield AMRC and EPSRC)
  Dr M Marshall, Dr P Crawforth
Applications accepted all year round
Start date. 3 September 2018. Stipend. Tax free stipend of £18,000 per year, plus all tuition fees paid at UK/EU rates. Project Description.
  Streptomyces venezuelae a next-generation cell-factory for synthetic biology
  Dr S Moore
Application Deadline: 1 February 2019
Streptomyces venezuelae a next-generation cell-factory for synthetic biology. Synthetic biology is beginning to explore new cell-factories for opportunities including biofuels and drugs.
  Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Applications accepted all year round
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas.
  Towards new antibacterial drugs to treat infections caused by multidrug-resistant bacteria: identification and characterization of novel natural product antibiotics
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A O'Neill
Applications accepted all year round
The World Health Organization (WHO) has declared antimicrobial drug resistance one of the greatest problems currently facing human health, and the situation is especially grave in the case of infections caused by bacterial pathogens.
  (BBSRC DTP) Characterization of P450 peroxygenases and their applications in alkene/biofuel production
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2019
The project involves characterization of P450 peroxygenase enzymes, a class of the P450 enzymes which naturally use hydrogen peroxide rather than redox partner systems to drive catalysis.
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