Imperial College London Featured PhD Programmes
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prostate cancer PhD Projects, Programs & Scholarships

We have 29 prostate cancer PhD Projects, Programs & Scholarships

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  Towards the development of an effective vaccine for advanced prostate cancer
  Dr S McArdle
Applications accepted all year round

Funding Type

PhD Type

Prostate cancer is the second most frequent cancer in men. Patients with a localized disease are treated with local therapies such as prostatectomy or radiation therapy, whereas patients with metastatic disease are treated with androgen deprivation therapies (ADT).
  Transcriptional heterogeneity and resistance to therapy in prostate cancer
  Dr D. Goode
Applications accepted all year round

Funding Type

PhD Type

Androgen deprivation therapy (ADT) is a standard treatment for prostate cancer that works well in many cases but rapidly fails in others.
  Ultrasensitive prostate cancer screening based on miRNA sensing from whole blood
  Prof J Edel
Applications accepted all year round

Funding Type

PhD Type

Current tests for the diagnosis, prognosis and stratification of prostate cancer suffer from two main drawbacks, being either invasive (requiring tissue biopsies) or inaccurate and therefore unreliable.
  The role of bone marrow fat in advance prostate cancer using bioengineered humanised models
  Dr N Bock
Application Deadline: 1 July 2020

Funding Type

PhD Type

SYNOPSIS. This highly innovative PhD project focuses on one of the key challenges in the fields of cancer research and translational medicine, which is to ‘make the mouse organism more human’.
  Targeting perivascular macrophages to enhance the efficacy of immunotherapy in prostate cancer
  Prof CE Lewis, Dr M Muthana
Applications accepted all year round

Funding Type

PhD Type

Immunotherapies like checkpoint inhibitors do not work well in most prostate cancer patients, with only a small group showing durable responses.
  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  mRNA translation reprogramming and metabolic re-wiring in response to ribosome-targeted therapies
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Increased synthesis and activity of ribosomes are associated with oncogenesis downstream of the major oncogenes including MYC, RAS and PI3K.
  Structure-property relationship in solid tumours – An integrated experimental and computational approach towards more effective early cancer diagnosis
  Dr Y Chen, Prof RL Reuben
Applications accepted all year round

Funding Type

PhD Type

Biological tissue often has unique three-dimensional hierarchical microstructures and morphologies, constantly evolving through their development and patho-physiological stages.
  Computational simulation of tumour formation and progression
  Dr D. Goode
Applications accepted all year round

Funding Type

PhD Type

Tumours comprise a complex mix of related but distinct cellular subpopulations that both compete and complement one another. These dynamics strongly influence how and when a tumour forms as well as its response to therapy, however there are hard to observe directly.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  An intelligent scheme to identify novel drug targets through analysing the DNA repairome in drug resistant cancer?
  Research Group: Biomedical Research Group
  Prof C Parris
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  A ‘Metastasis-On-A-Chip’ Microphysiological Model of Cancer Metastasis to Bone
  Dr M Amer, Dr V Pensabene, Prof F Meldrum
Application Deadline: 1 July 2020

Funding Type

PhD Type

Bone is a frequent site of cancer metastases and usually indicates poor clinical prognosis. Metastasis of tumour cells in the bone marrow is a dynamic process, and cell behaviour is regulated by three-dimensional (3D) cell-cell and cell-matrix interactions with its microenvironment.
  Mathematical Modelling of Cancer-Cell Transmigration Through Blood Vessels
  Dr F Spill
Applications accepted all year round

Funding Type

PhD Type

Cancer rarely kills through the primary tumour in which cancer arises, e.g. the prostate in prostate cancer. Instead, cancer cells may travel through the vasculature and colonialize distant organs – a process termed metastasis.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  Transglutaminase 2 (TG2) as a novel cancer biomarker and target for chemotherapy
  Research Group: Biomedical Research Group
  Dr P Coussons, Dr C Pike
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
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