Centre for Cancer Research and Cell Biology
Dr E Allott, Dr S Jain, Dr G Prue
20 January 2019
There are currently no well-established modifiable risk factors for prostate cancer. Some evidence suggests that obesity is linked to more aggressive prostate cancer and worse outcomes, but studies are inconsistent and mechanisms are not understood.
Prostate cancer is the most prevalent cancer diagnosed in men across Europe and northern America. In many men the cancer is slow-growing and not life-threatening but in a few the disease progresses rapidly with few effective treatment options and as a consequence poor prognosis.
Institute of Cardiovascular and Medical Sciences
Prof G Baillie, Dr J Edwards
7 January 2019
Supervisors. Prof George Baillie. Dr Joanne Edwards. Dr Ralf Hoffmann. PhD project summary. Emerging evidence demonstrates that human helicases like DHX9 could act as hubs in the cellular networks to coordinate cellular stress responses for survival or to trigger cell death.