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We have 383 protein PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
protein PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 383 protein PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Bifunctional small molecules beyond PROTACs: Proximity-inducing new downstream chemistries to rewire cell signalling
Proteolysis targeting chimeras (PROTACs) are a popular class of bifunctional molecules that simultaneously engage a target protein on one end and an E3 ubiquitin ligase on the other end, forming a ternary complex that facilitates the rapid ubiquitylation and subsequent degradation of the target protein. Read more
Polymer-engineering nanocages for protein delivery
Protein therapeutics are a fast-acting and potent class of medicine with remarkable success in the treatment of several relevant disorders. Read more
Structure and function of Batten disease proteins
The neuronal ceroid lipofucscinoses are a group of inherited neurodegenerative disorders with primarily childhood onset. The most common form, also known as Batten disease or CLN3 disease, is caused by recessively inherited mutation in the CLN3 gene. Read more
Enhancing Protein Thermal Stability for Melt Processing
Protein therapeutics are an important class of medicines with renowned efficacy in the treatment of several relevant disorders. Despite significant advantages, protein delivery remains a significant challenge. Read more
The mechanism of regulation of protein synthesis via eIF2 molecular complexes
Control of protein synthesis is critical for normal metabolism, development and responses to stress. One major pathway is called the integrated stress response (ISR) and centres on translational control of the general protein synthesis factor eIF2B via the phosphorylation of eIF2 [1,2]. Read more
High moisture extrusion technology assisted by enzymatic protein-protein crosslinking approach to improve the texture quality of plant-based meat analogues and eliminate the need for additives
We are looking for applicants with a degree in food science, food technology, food processing, food engineering, or similar applied undergraduate discipline. Read more
Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation
Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more
MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells
The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. . Read more
A bioinformatics approach to understanding protein solubility tags.
The crowded environment of a cell cytoplasm reveals that proteins and other biological molecules co-exist at high macromolecular concentrations. Many… Read more
Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials
Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more
Deep learning-based classification of proteins represented by Structural Alphabets to identify potential drug targets
- This project does not require any previous knowledge in Biology -. Proteins are the building blocks of all living organisms’ cells. Read more
New protein modification chemistries for studying protein structure and function
Chemically modified proteins can be used to understand, treat, and diagnose disease. However, relatively few chemical reactions can be used to modify proteins, severely limiting the diversity and applications of new technologies. Read more
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Analysis of protein S-acylation with modern mass spectrometry techniques
We are seeking a PhD student to study protein post translational modifications (PTMs) with native mass spectrometry. Ideal applicants will have experience in cell biology/biochemistry and/or mass spectrometry/analytical chemistry. Read more
Engineering Protein Nanocompartments for Biotechnological Applications
Protein nanocompartments have board applications as catalytic nanoreactors and as carriers for therapeutics delivery. They are self-assembled protein-based supramolecules that have spherical and hollow architectures. Read more
Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
Oxidative protein folding (protein folding and disulphide bond formation) is important for function and stability of many proteins. Read more