Protein biologicals have great potential for the effective treatment of a wide range of diseases. However, aggregation and instability are inherent issues with all protein pharmaceuticals, which is a problem that can limit their utility and developability.
University of Dundee, MRC Protein Phosphorylation and Ubiquitylation Unit, Dundee, United Kingdom. Dr. Yogesh Kulathu. Protein degradation is a fundamental process that is important for timely elimination of damaged proteins.