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protein aggregation PhD Projects, Programs & Scholarships

We have 16 protein aggregation PhD Projects, Programs & Scholarships

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We have 16 protein aggregation PhD Projects, Programs & Scholarships

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Harnessing cellular safety programs to prevent ageing

Ageing is a major challenge for individuals and the whole of society. Notably, ageing is a main risk factor for developing diseases such as cancer, heart disease, diabetes and neurodegeneration. Read more

(BBSRC DTP) Chaperones and the response to protein misfolding stress

Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more

Does SUMO protease SENP3 play a role in α-synuclein aggregation and toxicity?

Pathogenic causes for progressive loss of dopaminergic neurons along with protein aggregates termed Lewy bodies in the substantia nigra in (SN) Parkinson’s disease (PD) are not yet understood. Read more

Control of protein self assembly by biological ions

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

SELF-FUNDING MSc BY RESEARCH PROJECT: Underlying mechanism of thrombogenesis in patients with severe coronavirus disease 19 (COVID-19)

Severe coronavirus disease 19 (COVID-19) is a disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Patients with COVID-19 are at significantly increased risk of thrombosis, which can be a challenge to manage and is associated with elevated mortality and morbidity. Read more

Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

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