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We have 52 protein crystallography PhD Projects, Programmes & Scholarships

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protein crystallography PhD Projects, Programmes & Scholarships

We have 52 protein crystallography PhD Projects, Programmes & Scholarships

Introducing Artificial Metalloenzymes to Whole-Cell Biocatalysis

Background. Whole-cell biocatalysis is an attractive and cost-saving alternative to the use of purified enzymes. Given that the range of natural enzymes is limited, the potential of artificial metalloenzymes (ArMs) to create biocatalytic novelty is huge. Read more

Functional and structural characterisation of glycosyltransferases involved in protein mannosylation

Glycosylation is one the most abundant post-translational modifications and an evolutionary indicator. indeed the increasing complexity of host-pathogen and organism-environment interactions, amongst others, is reflected in the newly-reported ability of prokaryotes (e.g. Read more

Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more

The identification of allosteric inhibitors of high value therapeutic targets

This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Molecular characterization of suicidal phage-resistance mechanisms in bacteria

Additional Supervisor. Dr Abhinav Koyamangalath Vadakkepat. Importance . The proliferation of antibiotic resistance (AMR) is a formidable health challenge, accounting for 700,000 deaths annually1,2. Read more

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