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protein crystallography PhD Projects, Programs & Scholarships

We have 60 protein crystallography PhD Projects, Programs & Scholarships

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  New ways to look at enzyme structures
  Dr P C E Moody, Dr J Basran
Application Deadline: 6 January 2019
Metal-catalysed activation of oxygen in biology is achieved using either copper or iron. In the case of iron, this includes the heme-containing enzymes which activate oxygen.
  MRC DiMeN DTP: Dissecting INPP5K function: cell biology, structural determination by X-ray crystallography and enzymology of a key protein implicated in muscular dystrophy, insulin signalling, spastic paraplegias and Parkinsonism
  Dr L Swan, Dr S Antonyuk, Dr M Stagi
Application Deadline: 21 January 2019
The Swan laboratory (https://www.researchgate.net/profile/Laura_Swan), specialists in phosphoinositide lipid biology and the cell biology of membrane trafficking, in collaboration with international teams of clinicians and scientists, have recently discovered that mutations in a specific phosphatase cause a congenital muscular dystrophy with short stature, brain and eye manifestations (papers.
  Molecular basis of pathogenesis: Structure based design of novel therapeutics for the treatment of infectious diseases
  Prof R L Brady
Applications accepted all year round
Through the study of protein structure, primarily using protein crystallography but also electron microscopy and small-angle X-ray scattering, we aim to probe crucial biomolecular interactions central to a variety of diseases.
  Mechanism of transmembrane receptor activation
  Dr M Hyvonen
Applications accepted all year round
Applications are invited for a PhD position, starting in October 2019, in the group Dr Marko Hyvonen at University of Cambridge (http://hyvonen.bioc.cam.ac.uk/) to study the mechanism of transmembrane signalling by TGFbeta family growth factors.
  (BBSRC DTP) Characterization of P450 peroxygenases and their applications in alkene/biofuel production
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2019
The project involves characterization of P450 peroxygenase enzymes, a class of the P450 enzymes which naturally use hydrogen peroxide rather than redox partner systems to drive catalysis.
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 11 January 2019
It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  The importance of metal binding for the function of rice proteins that interact with pathogen effectors
  Prof C Dennison
Application Deadline: 11 January 2019
Global demand for food is rising and plant pathogens are one of a number of major threats to crop harvests. Plant pathogens produce effector proteins that remodel host cell processes for the benefit of the pathogen, resulting in disease.
  (BBSRC DTP CASE) Driving enzymatic carboxylation using supercritical CO2
  Prof D Leys, Dr S Hay, Prof I Larrosa
Application Deadline: 31 January 2019
The use of CO2 as a chemical feedstock is attractive for various reasons, not least as a means to address the desirable reduction of global CO2 levels.
  Drug discovery and Chemical-Biology Approaches Against Parasites that cause Neglected Tropical Diseases.
  Dr T Smith
Application Deadline: 14 December 2018
This proposal is aimed at students wanting to work at the interface of chemistry and biology.
  Mitochondrial protein quality control and ageing - Interaction of prohibitins with m-AAA proteases at the inner mitochondrial membrane
  Dr A Winter
Application Deadline: 12 December 2018
Mitochondrial protein quality control and ageing - Interaction of prohibitins with m-AAA proteases at the inner mitochondrial membrane.
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