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protein crystallography PhD Projects, Programmes & Scholarships

We have 58 protein crystallography PhD Projects, Programmes & Scholarships

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We have 58 protein crystallography PhD Projects, Programmes & Scholarships

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Molecular mechanisms of the ubiquitin system

How does ubiquitin achieve specificity in regulating virtually all aspects of eukaryotic homeostasis? A key point is the action of E3 ubiquitin ligases (E3Ls), the most diversified class of enzymes in the ubiquitin system. Read more
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EASTBIO Probing the mechanism and dynamics of Staphylococcus aureus m1A22-tRNA methyltransferase

  Research Group: Biomedical Sciences Research Centre
S. aureus has been a leading cause of healthcare- and community-associated infections worldwide, with a number of patients infected with methicillin-resistant S. Read more

Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Candidates are invited to join the Kadri Lab where our research focuses on developing innovative chemical approaches for the discovery of novel therapeutics to address unmet global health needs. Read more
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EASTBIO Disrupting bacterial biofilms with peptide-coated hydrogels

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. Biofouling is the accumulation of microorganisms in a surface, ultimately causing degradation and decay. If devices are in contact with water and moisture it will occur to ships, medical devices, and several instruments employed in manufacturing. Read more

In silico glycosylation of AlphaFold protein structural models.

Background. The recent release of the AlphaFold Protein Structure Database by DeepMind and EMBL-EBI has made available to the scientific community highly accurate structural predictions for 20,000 human proteins and those from 20 other biologically relevant organisms. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Molecular level understanding of Mycobacterium tuberculosis

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

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