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We have 13 protein engineer PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
protein engineer PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 13 protein engineer PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Polymer-engineering nanocages for protein delivery
Protein therapeutics are a fast-acting and potent class of medicine with remarkable success in the treatment of several relevant disorders. Read more
Engineering Protein Nanocompartments for Biotechnological Applications
Protein nanocompartments have board applications as catalytic nanoreactors and as carriers for therapeutics delivery. They are self-assembled protein-based supramolecules that have spherical and hollow architectures. Read more
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The physics and structural biology of supramolecular protein self-assembly in meiotic chromosome synapsis
Research Group:
Institute of Cell Biology
One of the largest protein structures in the cell is the synaptonemal complex (SC), which synapses together homologous chromosomes to facilitate their recombination during meiosis. Read more
Self-Navigating Nanocarriers for Intracellular Protein Delivery
Protein-based therapeutics have shown remarkable success in modulating extracellular targets; however, effective intracellular delivery remains a key challenge in biotherapeutics. Read more
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Engineering nuclear mechanotransduction across the nuclear pore complex (NPC) through molecular design
Communication between the cytoplasm and the nucleus is crucial to maintain cellular homeostasis. The nuclear pore complex (NPC) is a large multi-protein pore, embedded within the nuclear envelope membrane, that acts as the main gateway in and out from the nucleus. Read more
Design, construction and testing of recombinant protein production systems for industrial biotechnology applications.
The production of recombinant biopharmaceuticals, e.g., antibody fragments and growth hormones, is a billion-dollar industry, with many therapeutic proteins being expressed in the bacterium Escherichia coli [1]. Read more
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Engineering enzyme replacement therapies using geometric deep learning
Research Group:
Institute of Quantitative Biology, Biochemistry and Biotechnology
Metabolic enzymatic deficiencies (MEDs) disrupt cell physiology, either by preventing the production of essential metabolic intermediates or by causing the accumulation of toxic levels of substrates. Read more
Stress responses in crops and sustainable production of chemicals and biomass
The project aims at elucidating several aspects of the control of plant stress responses to identify environmentally friendly forms of plant protectants and phytopharmaceuticals, leading to enhanced crop yields and solutions for animals and human health. Read more
Optimization of the Potency and Specificity of Engineered Regulatory T Cells to Treat Inflammatory and Fibrotic Liver Diseases
The prevalence of chronic liver disease, the 5th most common cause of death in the UK is rising sharply mainly due to the increasing load of viral hepatitis, alcohol- related liver disease and non-alcoholic fatty liver. Read more
Engineering Virus-Like Particles (VLPS) for the Next-Generation Vaccines
Virus-like particles (VLPs) are molecules that mimic viruses and will trigger immune response when introduced into body. As they do not contain any viral genetic material, they are not infectious. Read more
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Building a plant-based carboxysome to improve photosynthesis
Supervisors. Dr. Douglas Orr. Dr. Marjorie Lundgren. . Project Description. Cyanobacteria have evolved elegant approaches to carrying out highly efficient photosynthesis in low CO. Read more
Antimicrobial resistance and gene regulation in Enteroaggregative Escherichia coli.
Enteroaggregative Escherichia coli (EAEC) is a major cause of diarrhoeal disease in industrialized and non-industrialized countries and has been shown to be the cause of travellers’ diarrhoea and persistent diarrhoea in children and HIV patients. Read more
Design and engineering of peptides and proteins to create artificial metalloenzymes
The Rhys lab is an exciting new lab looking to recruit new students to design and engineer peptides and proteins for new applications (. Read more
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