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We have 102 protein engineering PhD Projects, Programmes & Scholarships

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protein engineering PhD Projects, Programmes & Scholarships

We have 102 protein engineering PhD Projects, Programmes & Scholarships

Protein engineering enzymes for Industry

Project Overview. We are interested in key features of the protein sequence - structure - function relationship, and how this information can be translated to health. Read more

Design of metamorphic proteins for stimuli-responsive nanomaterials

Project Description. The classic structure-function paradigm of proteins contends that a protein exhibits a single well-defined folded structure that gives rise to its biological function. Read more

Structural biology tools to investigate and target ubiquitin system proteases in cancer

Ubiquitination targets proteins for degradation and regulates virtually all cellular signalling pathways in eukaryotes. The human genome encodes over 50 ubiquitin specific proteases (USPs) that cleave ubiquitin from modified proteins to salvage them from proteasomal degradation. Read more

EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more

DogDots: a new approach to labelling of membrane proteins for tomographic analysis

Membrane proteins are crucial to cellular function, such as recognition of – and interaction with – the extracellular environment and neighbouring cells, and controlling membrane dynamics, cellular signalling and transport of molecules and ions across membranes. Read more

Engineering Developable Biopharmaceuticals

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Synthetic Protein-Transporters for Enhanced Transduction Activity

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more
Last chance to apply

Exploiting lectin-glycan interactions to develop allergen trapping materials to manage asthma

Asthma affects more than 300 million people worldwide (Lancet 2023; 401. 858–73) in the UK, around 12% population have been diagnosed with asthma where the estimated total cost to NHS is ~£1.5 billion. Read more
Last chance to apply

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Predicting the Colloidal Properties of Recombinant Protein in Solution Using Molecular Dynamics Simulations

Recombinant proteins are increasingly being used as biotherapies and vaccines to treat or prevent a range of different diseases. Protein behaviour in solution can directly affect how they are manufactured and stored, and how effective they are after administration to patients. Read more

MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more

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